Sentences with phrase «epithelial cell proliferation»
Effects of dietary wheat - bran fiber on rectal epithelial cell proliferation in patients with resection for colorectal cancers.
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Intestinal epithelial cell proliferation is dependent on the site of massive small bowel resection
In human gastric tissue, however, gastric epithelial cell proliferation is significantly higher but apoptotic indices are lower among persons colonized with cag + compared to cag - strains or uninfected persons leading us to postulate that reduced rates of cell loss, when accompanied by hyperproliferation, may heighten retention of mutagenized cells, which could predispose towards cancer.
However, the regulatory mechanisms of mammary epithelial cell proliferation during pregnancy have been unclear.
«The inflammasome in turn activates the enzyme caspase - 1, which then produces two proteins (IL - 1β and IL - 18) that play important roles in the GI tract, including activation of immune cells, induction of antimicrobial peptides, and regulation of epithelial cell proliferation.»
Not exact matches
Transient Silencing of 14 -3-3sigma promotes proliferation of p63 - positive progenitor cells isolated from human breastmilk in mammary epithelial cell culture.
Secretion of the hormones estrogen and progesterone set the stage for dramatic changes that take place in the breast during pregnancy: a massive proliferation of mammary epithelial cells, and the formation of thousands of ductal structures, which support milk production and transport during lactation.
In cell culture, high expression levels of GPR161 induced proliferation of mammary epithelial cells, disrupted the acinar structures formed by these cells, and enhanced their invasive capacity.
Immunohistochemical stainings of Ki67 and pancytokeratin (Ki67 is stained brown, pancytokeratin is stained pink) indicate proliferation of hepatocytes (arrowheads) and biliary epithelial cells (arrows) in TAK1 / RIP3 - deficient mice.
Collectively, these results suggest that Nrk negatively regulates the estrogen - dependent proliferation of mammary epithelial cells, the disruption of which leads to breast tumors.
The absence of tumors in virgin Nrk mutant mice strongly suggests that the tumorigenesis is closely related to the proliferation of mammary epithelial cells during pregnancy.
In Nrk mutant mice, therefore, mammary tumorigenesis was proposed to be triggered by a combination of dysregulation of proliferation in mammary epithelial cells and excessive blood estrogen.
This suggests that Nrk is expressed in mammary epithelial cells late in pregnancy in order to terminate their proliferation.
During pregnancy, the elevated blood estrogen level induces the proliferation of mammary epithelial cells, leading to the development of the mammary gland in preparation for lactation.
This distribution helps to maintain the health and rapid proliferation rate of adult epithelial stem cells using MimEX ™ Tissue Model Systems.
MicroRNA -7-5p regulates the proliferation and migration of intestinal epithelial cells by targeting trefoil factor 3 via inhibiting the phosphoinositide 3 - kinase / Akt signalling pathway.
miR - 34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3.
MiR - 514a - 3p inhibits cell proliferation and epithelial - mesenchymal transition by targeting EGFR in clear cell renal cell carcinoma.
In a first set of experiments, postdoctoral researcher and co-lead author Max - Felix Häring found that insulin increased the proliferation of mouse epithelial tumor cells in culture, as expected.
Effects of microRNA - 211 on proliferation and apoptosis of lens epithelial cells by targeting SIRT1 gene in diabetic cataract mice.
ANXA1 affects cell proliferation, invasion and epithelial - mesenchymal transition of oral squamous cell carcinoma.
Jens - Christian Roeper (Eaton, MPG)-- «The influence of cell mechanics, cell - cell interactions and proliferation on epithelial packing» (2009)
Reeh KA, Cardenas KT, Bain VE, Liu Z, Laurent M, Manley NR, Richie, ER (2014) Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis.
Smyd3 function is required for the activation of oncogenic pathways, cell proliferation and epithelial to mesenchymal transition during tumorigenesis.
In particular, they are focused on studying the functional role and molecular mechanisms of cellular senescence in both of these events, and how a deregulation of normal epithelial stem cell proliferation is involved.
For most of the cancer cells, 45 — 100 nM RIPK2 inhibitor 1 inhibited > 70 % of the proliferation of colon and blood cancer cells while preserving the proliferation of normal Rat - 1 and ModeK intestinal epithelial cells (Fig. 6A).
In addition to its structural role in epithelial junctions, beta - catenin activates TCF -4-mediated transcription of genes required for cell proliferation.
Intestinal permeability was assessed by Ussing chamber; epithelial cell (EC) ultra-structure by electron microscopy; RNA expression of genes coding for junctional proteins by Q - real - time PCR; immune response by in - vitro antigen - specific T - cell proliferation and cytokine analysis by cytometric bead array; intestinal microbiota by fluorescence in situ hybridization and analysis of systemic antibodies against intestinal microbiota by surface staining of live bacteria with serum followed by FACS analysis.
The group who consumed soy protein had significant increases in the proliferation of epithelial cells in the breasts.