The ΔN isoforms of p63 may also serve as stem cell markers in a variety of
epithelial cell types, including endometrium [30], cervix [31], breast [32], prostate [33], and in stratified squamous epithelium [21,34].
The stem cells in the bulge are multipotent epithelial stem cells, and can become, or differentiate into, all
the epithelial cell types in the follicle (including hair follicles, epidermis, and sebaceous glands)(Oshima et al., 2001).
«An exciting outcome of this study was the allocation of known and novel specific sensory molecules associated with
each epithelial cell type,» said Rogel.
Not exact matches
Stem
cells have also been identified in human milk, and have the potential to differentiate into mammary
epithelial lineages under mammary differentiation conditions in vitro, as well as other
cell types in corresponding microenvironments, including bone
cells, brain
cells, liver
cells, pancreatic beta
cells and heart
cells.
The receptor is often expressed on
epithelial cells, the
type of
cells that turn cancerous, and it promotes
cell survival.
They concluded from that evidence that these specialized RNAs were coming from two
types of
epithelial cells that line the GI tract.
So Welham's team set out to engineer vocal fold mucosae in the lab using the two main
cell types that make up the tissue — connective fibroblasts, which form the main body, and
epithelial cells, which line the surface.
«And those are the
types of patients, who potentially would eventually go to the intensive care unit, that we think could be treated early in infection with Accolate or Singulair to prevent infection of these
epithelial cells and prevent lethal infection.»
However, compared to other avian influenza viruses, the attachment to
epithelial cells by H7N9 in the bronchioles and alveoli of the lung was more abundant and the viruses attached to a broader range of
cell types.
The research team was also able to shed more light on the role of Paneth
cells — a
type of
cell found in the
epithelial lining of the small intestine.
Heaton et al. now report that a special
type of
epithelial cell in the lungs of mice — called club
cells — survive influenza infection.
The EMT is a biological process wherein
epithelial cells (
cells that line the cavities and surfaces of blood vessels and organs) become mesenchymal (skeletal) stem
cells that can move throughout the body and differentiate into a variety of
cell types.
In most cases, infected
epithelial cells are quickly killed by CD8 +
cells, a
type of white blood
cells; only occasionally does the infection overwhelm the immune system, resulting in a lesion.
Basically, when you look at different
types of
cells, such as fibroblasts, which form connective tissue, or
epithelial cells, from saliva, you see general correlations within a person.
Gut microbiota that live in the outer regions of the mucus and remain a safe distance from
epithelial cells provide a benefit to the host, but Chassaing and Gewirtz hypothesize that microbiota that encroach upon host
cells drive chronic inflammation that interferes with the normal action of insulin, promoting
type 2 diabetes.
In the new study, the researchers explored the role of
cell shape in two vastly different
types of
epithelial cells — human bronchial
epithelial cells grown in the lab and
cells within the living embryo of the fruit fly — and observed them as they matured over time.
The
epithelial stem
cells, when implanted into immunocompromised mice, regenerated the different
cell types of human skin and hair follicles, and even produced structurally recognizable hair shaft, raising the possibility that they may eventually enable hair regeneration in people.
«All
epithelial cells — and that's the
cells that make up most of the organs in our bodies — can do this, so you could imagine that this
type of local chamber could be forming transiently in many different parts of the body, whenever
cells need to self - organise and communicate,» Gilmour says.
First, a hair follicle contains
epithelial cells — a
cell type that lines the body's vessels and cavities — as well as a specific kind of adult stem
cell called dermal papillae.
Briefly, single -
cell suspensions of C57BL / 6 KO and wild -
type lymphocytes, which had undergone a 96 hr in vitro boost with γ - irradiated (3,000 rad) BALB / c stimulator lymphocytes, were added to 96 - well microtiter plates (Corning Inc., Corning, NY) along with 2 × 104 51Cr - labeled BALB / c corneal
epithelial or endothelial
cells in a total volume of 200 μl / well.
Mechanical properties of many different
cell types including glial
cells, platelets, cardiocytes, macrophages, endothelial
cells,
epithelial cells, fibroblasts, bladder
cells and more have been determined using F - d spectroscopy.
Differential Response of the Human Renal Proximal Tubular
Epithelial Cell Line HK - 2 to Shiga Toxin
Types 1 and 2.
Endothelial Monocyte Activating Polypeptide II Disrupts Alveolar
Epithelial Type II to
Type I
Cell Transdifferentiation.
Our Intestine - Chip also allows researchers to culture intestinal
epithelial cells alongside other
cell types, such as immune
cells, and analyze how these different
cell types interact.
First, most currently generated organoids mainly contain
epithelial cells and are void of the many different
cell types that are essential for the morphology and functionality of the whole organ.
13 - cis - Retinoic acid specific down - regulation of angiotensin
type 1 receptor in rat liver
epithelial and aortic smooth muscle
cells.
Pharmacologic Effects of 2 - Methoxyestradiol on Angiotensin
Type 1 Receptor Down - Regulation in Rat Liver
Epithelial and Aortic Smooth Muscle
Cells % U http://www.sciencedirect.com/science/article/pii/S1550857912000484.
Calcitonin gene - related peptide;
Type II alveolar
epithelial cell; Oxidative stress; Lung injury; Wnt7b; β - catenin
The researchers conclude that this could be owing to the bone marrow - derived MSCs being able to act as progenitor
cells, similar to alveolar
epithelial type II
cells.
Data from the laboratory shows that signals from these molecules through their receptors control the activities and long - term survival of T
cells, as well as affecting the activities of other
cell types including dendritic
cells, macrophages, and
epithelial cells.
In a collaborative study published in Nat Med, a Fleming Marie Curie Fellow revealed that aerosolized delivery of active Thyroid Hormone (TH) resolved pulmonary fibrosis in two mouse models through a mechanism that involved improvement of mitochondrial biogenesis and mitophagy in alveolar
type II
epithelial cells.
Weaver also said that the predictions made by jamming models resemble what biologists call extrusion, a process by which dead
epithelial cells are squeezed out of crowded tissue — the disfunction of which has recently been implicated in certain
types of cancer.
Most
types of cancer arise from
epithelial cells.
Similar to primary keratinocytes, long - term — cultured squamous
cell carcinoma (30) and many other
epithelial cancer
cells (30, 31) can also form different
types of clones in culture.
For example, ΔNp63α is expressed in
epithelial stem
cells, while TAp63α is expressed in fully differentiated
cell types.
Calcitonin Gene - Related Peptide Enhances the Expression of Signaling Molecules of the Wnt 7b / Beta - Catenin Pathway in Rat
Type II Alveolar
Epithelial Cells Under Hyperoxia
Calcitonin Gene - Related Peptide Enhances the Expression of Signaling Molecules of the Wnt 7b / Beta - Catenin Pathway in Rat
Type II Alveolar
Epithelial Cells Under Hyperoxia Hyperoxic lung injury is characterized by epithelial cell death and leukocyte infiltration / inflammation in
Epithelial Cells Under Hyperoxia Hyperoxic lung injury is characterized by
epithelial cell death and leukocyte infiltration / inflammation in
epithelial cell death and leukocyte infiltration / inflammation in the lung.
Creating human lung
epithelial cells in the lab has been a challenge, and lineage - specific reporters, which indicate each
cell's specific
type, are key to understanding lung
epithelial stem
cell development.
We also found that several carriage strains had lost their
type IV pili and that this loss correlated with reduced tumor necrosis factor alpha (TNF - α) expression when cultured with
epithelial cells.
Meyer et al 2009 [24] have recently shown that iPS
cells can be differentiated towards retinal
cell types whilst a paper by Buchholz et al 2009 [25] has shown that human iPS
cells can be differentiated into retinal pigment
epithelial cells which display functionality in vitro.
Intestinal
epithelial tuft
cells initiate
type 2 mucosal immunity helminth parasites.
Lauric Acid inhibited the viability of both cancer
cell types without altering the growth of MCF - 10A normal breast
epithelial cells, thus suggesting its specific potential to trigger antiproliferative effects in malignant
cells.
There are various
types of bladder tumors like squamous
cell carcinoma (arise in the
epithelial cells), adenocarcinoma (arise in the glandular epithelium), undifferentiated carcinoma, rhabdomyosarcoma (tumor of the striated muscle - form of fibers combined into parallel fibers like the skeletal and the cardiac muscles), fibroma (tumors made of fibrous or connective tissue.