Sentences with phrase «epithelial cell types»

The ΔN isoforms of p63 may also serve as stem cell markers in a variety of epithelial cell types, including endometrium [30], cervix [31], breast [32], prostate [33], and in stratified squamous epithelium [21,34].
The stem cells in the bulge are multipotent epithelial stem cells, and can become, or differentiate into, all the epithelial cell types in the follicle (including hair follicles, epidermis, and sebaceous glands)(Oshima et al., 2001).
«An exciting outcome of this study was the allocation of known and novel specific sensory molecules associated with each epithelial cell type,» said Rogel.

Not exact matches

Stem cells have also been identified in human milk, and have the potential to differentiate into mammary epithelial lineages under mammary differentiation conditions in vitro, as well as other cell types in corresponding microenvironments, including bone cells, brain cells, liver cells, pancreatic beta cells and heart cells.
The receptor is often expressed on epithelial cells, the type of cells that turn cancerous, and it promotes cell survival.
They concluded from that evidence that these specialized RNAs were coming from two types of epithelial cells that line the GI tract.
So Welham's team set out to engineer vocal fold mucosae in the lab using the two main cell types that make up the tissue — connective fibroblasts, which form the main body, and epithelial cells, which line the surface.
«And those are the types of patients, who potentially would eventually go to the intensive care unit, that we think could be treated early in infection with Accolate or Singulair to prevent infection of these epithelial cells and prevent lethal infection.»
However, compared to other avian influenza viruses, the attachment to epithelial cells by H7N9 in the bronchioles and alveoli of the lung was more abundant and the viruses attached to a broader range of cell types.
The research team was also able to shed more light on the role of Paneth cells — a type of cell found in the epithelial lining of the small intestine.
Heaton et al. now report that a special type of epithelial cell in the lungs of mice — called club cells — survive influenza infection.
The EMT is a biological process wherein epithelial cells (cells that line the cavities and surfaces of blood vessels and organs) become mesenchymal (skeletal) stem cells that can move throughout the body and differentiate into a variety of cell types.
In most cases, infected epithelial cells are quickly killed by CD8 + cells, a type of white blood cells; only occasionally does the infection overwhelm the immune system, resulting in a lesion.
Basically, when you look at different types of cells, such as fibroblasts, which form connective tissue, or epithelial cells, from saliva, you see general correlations within a person.
Gut microbiota that live in the outer regions of the mucus and remain a safe distance from epithelial cells provide a benefit to the host, but Chassaing and Gewirtz hypothesize that microbiota that encroach upon host cells drive chronic inflammation that interferes with the normal action of insulin, promoting type 2 diabetes.
In the new study, the researchers explored the role of cell shape in two vastly different types of epithelial cells — human bronchial epithelial cells grown in the lab and cells within the living embryo of the fruit fly — and observed them as they matured over time.
The epithelial stem cells, when implanted into immunocompromised mice, regenerated the different cell types of human skin and hair follicles, and even produced structurally recognizable hair shaft, raising the possibility that they may eventually enable hair regeneration in people.
«All epithelial cells — and that's the cells that make up most of the organs in our bodies — can do this, so you could imagine that this type of local chamber could be forming transiently in many different parts of the body, whenever cells need to self - organise and communicate,» Gilmour says.
First, a hair follicle contains epithelial cells — a cell type that lines the body's vessels and cavities — as well as a specific kind of adult stem cell called dermal papillae.
Briefly, single - cell suspensions of C57BL / 6 KO and wild - type lymphocytes, which had undergone a 96 hr in vitro boost with γ - irradiated (3,000 rad) BALB / c stimulator lymphocytes, were added to 96 - well microtiter plates (Corning Inc., Corning, NY) along with 2 × 104 51Cr - labeled BALB / c corneal epithelial or endothelial cells in a total volume of 200 μl / well.
Mechanical properties of many different cell types including glial cells, platelets, cardiocytes, macrophages, endothelial cells, epithelial cells, fibroblasts, bladder cells and more have been determined using F - d spectroscopy.
Differential Response of the Human Renal Proximal Tubular Epithelial Cell Line HK - 2 to Shiga Toxin Types 1 and 2.
Endothelial Monocyte Activating Polypeptide II Disrupts Alveolar Epithelial Type II to Type I Cell Transdifferentiation.
Our Intestine - Chip also allows researchers to culture intestinal epithelial cells alongside other cell types, such as immune cells, and analyze how these different cell types interact.
First, most currently generated organoids mainly contain epithelial cells and are void of the many different cell types that are essential for the morphology and functionality of the whole organ.
13 - cis - Retinoic acid specific down - regulation of angiotensin type 1 receptor in rat liver epithelial and aortic smooth muscle cells.
Pharmacologic Effects of 2 - Methoxyestradiol on Angiotensin Type 1 Receptor Down - Regulation in Rat Liver Epithelial and Aortic Smooth Muscle Cells % U http://www.sciencedirect.com/science/article/pii/S1550857912000484.
Calcitonin gene - related peptide; Type II alveolar epithelial cell; Oxidative stress; Lung injury; Wnt7b; β - catenin
The researchers conclude that this could be owing to the bone marrow - derived MSCs being able to act as progenitor cells, similar to alveolar epithelial type II cells.
Data from the laboratory shows that signals from these molecules through their receptors control the activities and long - term survival of T cells, as well as affecting the activities of other cell types including dendritic cells, macrophages, and epithelial cells.
In a collaborative study published in Nat Med, a Fleming Marie Curie Fellow revealed that aerosolized delivery of active Thyroid Hormone (TH) resolved pulmonary fibrosis in two mouse models through a mechanism that involved improvement of mitochondrial biogenesis and mitophagy in alveolar type II epithelial cells.
Weaver also said that the predictions made by jamming models resemble what biologists call extrusion, a process by which dead epithelial cells are squeezed out of crowded tissue — the disfunction of which has recently been implicated in certain types of cancer.
Most types of cancer arise from epithelial cells.
Similar to primary keratinocytes, long - term — cultured squamous cell carcinoma (30) and many other epithelial cancer cells (30, 31) can also form different types of clones in culture.
For example, ΔNp63α is expressed in epithelial stem cells, while TAp63α is expressed in fully differentiated cell types.
Calcitonin Gene - Related Peptide Enhances the Expression of Signaling Molecules of the Wnt 7b / Beta - Catenin Pathway in Rat Type II Alveolar Epithelial Cells Under Hyperoxia
Calcitonin Gene - Related Peptide Enhances the Expression of Signaling Molecules of the Wnt 7b / Beta - Catenin Pathway in Rat Type II Alveolar Epithelial Cells Under Hyperoxia Hyperoxic lung injury is characterized by epithelial cell death and leukocyte infiltration / inflammation inEpithelial Cells Under Hyperoxia Hyperoxic lung injury is characterized by epithelial cell death and leukocyte infiltration / inflammation inepithelial cell death and leukocyte infiltration / inflammation in the lung.
Creating human lung epithelial cells in the lab has been a challenge, and lineage - specific reporters, which indicate each cell's specific type, are key to understanding lung epithelial stem cell development.
We also found that several carriage strains had lost their type IV pili and that this loss correlated with reduced tumor necrosis factor alpha (TNF - α) expression when cultured with epithelial cells.
Meyer et al 2009 [24] have recently shown that iPS cells can be differentiated towards retinal cell types whilst a paper by Buchholz et al 2009 [25] has shown that human iPS cells can be differentiated into retinal pigment epithelial cells which display functionality in vitro.
Intestinal epithelial tuft cells initiate type 2 mucosal immunity helminth parasites.
Lauric Acid inhibited the viability of both cancer cell types without altering the growth of MCF - 10A normal breast epithelial cells, thus suggesting its specific potential to trigger antiproliferative effects in malignant cells.
There are various types of bladder tumors like squamous cell carcinoma (arise in the epithelial cells), adenocarcinoma (arise in the glandular epithelium), undifferentiated carcinoma, rhabdomyosarcoma (tumor of the striated muscle - form of fibers combined into parallel fibers like the skeletal and the cardiac muscles), fibroma (tumors made of fibrous or connective tissue.
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