Sentences with phrase «epithelial cells»

Heaton et al. now report that a special type of epithelial cell in the lungs of mice — called club cells — survive influenza infection.

We further confirmed that RCAS infected equivalent numbers of mammary epithelial cells in WAP - tva and MMTV - tva mice (Figure 4 — source data 1).

The human mammary epithelial cell line (HuMEC) was maintained in human basal serum - free medium (Life Technologies) with the HuMEC kit (Life Technologies).

MicroRNA -7-5p regulates the proliferation and migration of intestinal epithelial cells by targeting trefoil factor 3 via inhibiting the phosphoinositide 3 - kinase / Akt signalling pathway.

Researchers at the RIKEN Center for Developmental Biology in Kobe plan to generate replacement retinal pigment epithelial cells from iPS cells generated from patients suffering age - related macular degeneration.

We are studying these proteins in the intestine and liver in vivo, as well as in epithelial cell lines.

Chromosome - associated protein D3 promotes bacterial clearance in human intestinal epithelial cells by repressing expression of amino acid transporters.

Despite strong support for the proliferative and growth - promoting effects of estrogens on mammary epithelial cells from animal and experimental studies (78, 79), previous studies on the associations between estrogens and breast density showed largely null or inconsistent results.

He found that red ginseng extract improves the survival of human lung epithelial cells infected with influenza virus.

Her major scientific contributions have centered on defining the importance of mononuclear phagocyte function in resistance to infection and inflammation, defining the interaction of pathogens and commensal bacteria with epithelial cells in homeostasis and inflammation, and experimental reproducibility.

The study team assessed three sets of outcomes: a maturational index (MI) based on epithelial cells from the children's urogenital tissue; ultrasound measurements of uterine, ovarian and testicular volume, as well as breast - buds; and hormone concentrations seen in blood tests.

Obesity was positively associated with DNA damage in the breast epithelial cells of individuals whether or not they were BRCA mutation carriers, but the stronger effect was seen in the tissue of those who were BRCA mutation carriers.

In addition to LL - 37, ovine cathelicidin SMAP - 29 and porcine cathelicidin Protegrin - 1 were also shown to reduce HRV replication in airway epithelial cells in vitro.

Meyer et al 2009 [24] have recently shown that iPS cells can be differentiated towards retinal cell types whilst a paper by Buchholz et al 2009 [25] has shown that human iPS cells can be differentiated into retinal pigment epithelial cells which display functionality in vitro.

Stage I lactogenesis, or secretory initiation, occurs during pregnancy and is defined by the differentiation of mammary alveolar epithelial cells into specialized secretory cells, termed lactocytes (1).

The researchers painstakingly examined how Alix exercises these functions to promote the correct assembly and positioning of specialized intercellular junctions between epithelial cells called the tight junctions.

Sauerkraut is a good source of fermentable fiber aka prebiotics that is fuel for the commensal gut bacteria so that they can produce compounds (such as short chain fatty acids) that feed more commensal bacteria and feed gut epithelial cells which are required to make the gut barrier.

These findings uncover the mechanism by which normal epithelial cells recognize and eliminate oncogenic neighbors by cell competition.

It was also tested using the human gastric epithelial cell line GES - 1 (more here on how human cell lines are commonly used in research) which was incubated with GABA and then treated with ethanol to induce cell injury.

MAIT cells can kill bacterially infected epithelial cells in vitro.

This certainly applies to living tissues when multicellular assemblies such as epithelial cells achieve complex morphogenetic processes.

Using macrophages and a variety of epithelial cell types as models systems, his research employs genomic, proteomic, and cellular imaging approaches, coupled with computational biology strategies to identify the pathways modulated by nanoparticles and the implications of these pathways for human health.

Transient Silencing of 14 -3-3sigma promotes proliferation of p63 - positive progenitor cells isolated from human breastmilk in mammary epithelial cell culture.

In the first half of pregnancy secretory differentiation (the differentiation of alveolar epithelial cells into milk - secreting cells), ductal branching and lobular formation of the breast (mammogenesis) occur.

In the Intestine Chip, the epithelium forms villi - like projections lined by polarized epithelial cells that undergo multi-lineage differentiation similar to that of intestinal organoids, however, these cells expose their apical surfaces to an open lumen and interface with endothelium.

Time - lapse movie of zebrafish lens epithelial cells expressing GFP - histones and mCherry - zGem as they progress through the cell cycle.

In stark contrast to contemporary human influenza H1N1 viruses, the 1918 pandemic virus had the ability to replicate in the absence of trypsin, caused death in mice and embryonated chicken eggs, and displayed a high - growth phenotype in human bronchial epithelial cells.

(C) Degree of branching and number of mammary epithelial cell layers in the mammary tissue formed by mammary cells infected with miR - 150.

Here we describe a method for fabricating a primary human Small Intestine - on - a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies.

Intestinal epithelial cell proliferation is dependent on the site of massive small bowel resection

Zinc is essential to the cellular apparatus that holds epithelial cells together and thus helps protect our animals against their environment.

Using a crystal structure of a complex protein compound of botulinum neurotoxin, Rongsheng Jin, associate professor of physiology & biophysics at UC Irvine, and collaborators found that these compounds — called clostridial hemagglutinin (HA)-- bind with epithelial cell proteins in the intestines of patients, which initiates a process that disrupts the close intercellular seals so that the complex toxin molecules can slip through the epithelial barrier.

The article «Estrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors» is published ahead - of - print in the American Journal of Physiology — Lung Cellular and Molecular Physiology.

This is a scanning electron microscope image of retinal pigment epithelial cells derived from stem cells.

Work in our group is aimed to understand the cellular, molecular and genetic mechanisms that control the establishment and maintenance of epithelial cell polarity.

Reeh KA, Cardenas KT, Bain VE, Liu Z, Laurent M, Manley NR, Richie, ER (2014) Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis.

Calcitonin Gene - Related Peptide Enhances the Expression of Signaling Molecules of the Wnt 7b / Beta - Catenin Pathway in Rat Type II Alveolar Epithelial Cells Under Hyperoxia

These live microorganisms have proven health benefits and well - established safety, and have been tested for epithelial cell adhesion and / or resistance to low pH.

Additional research will show whether other epithelial cells such as skin also partake of this self - healing method.

Scientists study dorsal closure, which occurs during the development of the fruit fly Drosophila melanogaster, to gain insights into wound healing in humans, as both processes involve closing a gap in the skin by stretching the surrounding epithelial cells over it.

A recent in vitro study has suggested that the mechanism of lectin damage may occur by interfering with the repair of already - damaged epithelial cells.8