Sentences with phrase «epithelial cells expressing»

Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire.

MAIT cells are also activated by and kill epithelial cells expressing endogenous levels of MRI after infection with the invasive bacteria Shigella flexneri.

Time - lapse movie of zebrafish lens epithelial cells expressing GFP - histones and mCherry - zGem as they progress through the cell cycle.

Moreover, ablation of a STAT5A allele reduces tumor incidence in a mouse model of breast cancer in which mammary epithelial cells express T antigen (48).

Not exact matches

The receptor is often expressed on epithelial cells, the type of cells that turn cancerous, and it promotes cell survival.

«With Rudolph,» Farber says, «the coral DNA got inserted into a gene that is normally expressed in the nasal epithelial cells, the cells of his nose.

We show here that acidic mammalian chitinase (AMCase) is induced via a T helper - 2 (Th2)-- specific, interleukin - 13 (IL - 13)-- mediated pathway in epithelial cells and macrophages in an aeroallergen asthma model and expressed in exaggerated quantities in human asthma.

They found that infection of the narrowest airways of the lung by PIV3 alone caused moderate levels of inflammation, but after infection by PIV3 expressing RSV NS2, the epithelial cells lining the narrow airways were shed rapidly into the airway lumen.

Using animal models, Pickles has already found candidate molecular biomarkers that indicate if the epithelial cells in the tiniest airways are expressing the RSV NS2 protein.

«But what we've now shown is that RSV has an increased ability to cause airway obstruction because, during an RSV infection, the virus expresses a specific RSV - encoded non-structural protein, or NS2, in epithelial cells, causing the cells to shed from the airway lining and into the airway lumen.

In one experiment, the researchers created arrays of mammary epithelial cells and asked how adding one or more cells expressing low levels of the cancer gene RasG12V affected the cells around them.

But Raz and colleagues have found that TPRV1 is also expressed by epithelial cells of the intestines, where it is activated by epidermal growth factor receptor or EGFR.

The third, SFTPA2, affects a protein expressed only in the fluid that bathes the lung's epithelial cells.

The goal of the first experiment was to see whether lncRNAs are differentially expressed in prostate cancer by measuring total RNA from prostate cancer cell lines and normal epithelial prostatic cells using NCode human ncRNA array and SurePrint G3 human lncRNA microarrays.

This suggests that Nrk is expressed in mammary epithelial cells late in pregnancy in order to terminate their proliferation.

These differently expressed microRNAs may contribute to stem cell and epithelial (tissue cells) abnormalities in diabetic corneas.

MCF - 7 Cells Expressing Nuclear - associated Lysyl Oxidase - like 2 (LOXL2) Exhibit an Epithelial - to - Mesenchymal Transition (EMT) Phenotype and are Highly Invasive In Vitro.

Centriole assembly in CHO cells expressing Plk4 / SAS6 / SAS4 is similar to centriogenesis in ciliated epithelial cells.

SDF - 1 is expressed in synovial epithelial cells and it has been reported that persistent induction of CXCR4 by stromal derived factors, such as TGF - β led to SDF - 1 mediated accumulation of CD4 T cells within the rheumatoid joint [44].

Initial reprogramming efforts used adult mouse limbal progenitors (epithelial cells which express Sox2, Klf4, and Myc) which the group reprogrammed to iPSCs using embryonic stem cell CM (ESCM) supplemented with MAPK and GSK3 inhibitors as previously described [4, 5].

The IL -1-like cytokine IL - 33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel «alarmin»?

In chick embryos, skeletal muscle formation is initiated by migrating Delta1 - expressing neural crest cells that trigger NOTCH signaling and myogenesis in selected epithelial somite progenitor cells, which rapidly translocate into the nascent muscle to differentiate.

LIGHT can bind LTβR, a TNFR family molecule constitutively expressed on stromal cells, dendritic cells, macrophages, and some epithelial cells.

This suggests that Vanin - 1 expressed by epithelial cells exerts a control on immune responses.

For example, ΔNp63α is expressed in epithelial stem cells, while TAp63α is expressed in fully differentiated cell types.

The observations made herein are unlikely restricted to only PC3 cells as Du145 holoclones can also be serially passaged and sustain long - term propagation (31) and many other epithelial cancer cells form holoclones that also express CSC markers such as CD44 (30).

We note that our new results show that miR - 142 upregulates the expression of miR - 150 when miR - 142 is highly expressed and / or the Wnt signaling pathway is strongly stimulated in mammary epithelial cells.

We note that our results show that miR - 142 upregulates the expression of miR - 150 when miR - 142 is highly expressed and / or the WNT signaling pathway is strongly stimulated in mammary epithelial cells.

LARP7 was expressed at relatively high levels in the untransformed mammary epithelial cell lines (MCF10A and EpH4) and noninvasive breast cancer cell lines (MCF7, BT474, T74D, and ZR75B), but was markedly reduced in all four invasive and metastatic cancer lines examined (MDA - MB - 468, BT549, MDA - MB - 231, and MDA - MB - 435; Figure 1D).

Considering that miR - 142 is highly expressed in human BCSCs, but weakly expressed or undetectable in the stem / progenitor population of the mammary epithelial cells, our result suggest that the upregulation of miR - 142 and its enhancement of the miR - 150 expression seem to be especially relevant in the breast tumor progression in vivo.

In normal mammary tissues, LARP7 was highly expressed in the epithelial cells of the mammary lobuli and terminal ducts (Figure 1C).