Sentences with phrase «epithelial cells form»

Pancreatic Epithelial Cells Form Islet - Like Clusters in the Absence of Directed Migration.

Corresponding to the primary function of epithelial tissues, i. e. forming a barrier between compartments, epithelial cells form tight adhesions between each other, and display only lateral mobility, confined by the basement membrane.

Epithelial cells form tissue layers that cover our skin and the inner surfaces of most of our internal organs, while endothelial cells line the adjacent blood - transporting vessels and capillaries that support their functions.

Not exact matches

In cell culture, high expression levels of GPR161 induced proliferation of mammary epithelial cells, disrupted the acinar structures formed by these cells, and enhanced their invasive capacity.

The «dry» form is caused by natural deposits on the retina that gradually kill retinal pigment epithelial cells.

Similar patches and treatments have already been tested against the «wet» form — in which blood vessels invade and destroy the retinal pigment epithelial cells that nourish and support the photoreceptor cells that capture light.

Esrp1 and Esrp2 are active specifically in epithelial cells, which form the skin, the inner layers of the gut and lung, and other tissues in the body.

So Welham's team set out to engineer vocal fold mucosae in the lab using the two main cell types that make up the tissue — connective fibroblasts, which form the main body, and epithelial cells, which line the surface.

When this model was in its softest mode, normal (benign) mammary epithelial cells behaved normally within it, forming cellular structures referred to as acini that capture many key features of the normal in vivo mammary epithelium.

The images show how a growth factor caused cells to change forms and regroup from tight packs of epithelial cells to more mobile, loose arrays of mesenchymal cells — information useful for studying cancer and wound healing.

The drug treatment and radiation cause damage to the epithelial cells, which form part of the intestinal mucosal layer.

Similar patches have already had some positive results for the «wet» form, in which blood vessels invade and destroy the retinal pigment epithelial cells.

To test their idea for the dry form, Amir Kashani of the University of Southern California in Los Angeles and his colleagues coated 6 by 4 - millimetre slithers of polymer with retinal pigment epithelial cells they had grown, then transplanted these into four people.

During pregnancy, epithelial cells in the breasts proliferate and form structures that make milk.

It has been designed for treating the «dry» form of macular degeneration, caused by deposits on the retina gradually killing retinal pigment epithelial cells, which support light - capturing cells.

During pregnancy, hormonal signals cause epithelial cells lining the ducts to proliferate and form ball - like structures called alveoli, which is where milk is made when the baby is born.

Basically, when you look at different types of cells, such as fibroblasts, which form connective tissue, or epithelial cells, from saliva, you see general correlations within a person.

«All epithelial cells — and that's the cells that make up most of the organs in our bodies — can do this, so you could imagine that this type of local chamber could be forming transiently in many different parts of the body, whenever cells need to self - organise and communicate,» Gilmour says.

This shows hair shafts (arrows) formed by induced pluripotent stem cell - derived epithelial stem cells.

Thus, epithelial tumor cells must undergo phenotypical changes that allow them to breach the basement membrane, invade adjacent tissues and ultimately form distant metastases.

With the reference cell census data in hand, the research team is excited to conduct additional studies, including ones involving models or human patients with gastrointestinal conditions — Crohn's disease, ulcerative colitis, gastrointestinal cancers, forms of food allergy, etc. — aimed at identifying changes in gene expression and epithelial structure and function that could reveal new insights and opportunities for therapeutic development.

In the Intestine Chip, the epithelium forms villi - like projections lined by polarized epithelial cells that undergo multi-lineage differentiation similar to that of intestinal organoids, however, these cells expose their apical surfaces to an open lumen and interface with endothelium.

Sponge cells adhere to form tissue - like layers, but a true epithelial cell layer, characterized by aligned cell polarity, belt - form junctions and underlying basal lamina, is thought to be a eumetazoan innovation.

Third place went to Charlie Granger, a PhD candidate in optics, who used adaptive optics technology to show the natural fluorescence of retinal pigment epithelial cells, which form a layer only one cell deep, on the backside of the eye's light - sensitive retina.

Similar to primary keratinocytes, long - term — cultured squamous cell carcinoma (30) and many other epithelial cancer cells (30, 31) can also form different types of clones in culture.

The observations made herein are unlikely restricted to only PC3 cells as Du145 holoclones can also be serially passaged and sustain long - term propagation (31) and many other epithelial cancer cells form holoclones that also express CSC markers such as CD44 (30).

Epithelial cells are polarized - they have a top and bottom, which differ from one another in form and function.

Interestingly, long - term — cultured human epithelial cancer cells in clonal cultures also form holoclones, meroclones, and paraclones, and tumor cell holoclones have been hypothesized to harbor stem - like cells or cancer stem cells.

The intestinal epithelial cells (IECs) that line the gut form a robust line of defense against ingested pathogens.

This lining consists of a layer of epithelial cells that come together to form a barrier that is impenetrable to the nanoparticles, thereby necessitating the use of injections to be an effective form of treatment.

Last year, Mandriota and collaborators demonstrated that in a cancer mouse model, concentrations of aluminum in the amount of those measured in the human breast are able to transform cultured mammary epithelial cells, allowing them to form tumors and to metastasize.

(C) Degree of branching and number of mammary epithelial cell layers in the mammary tissue formed by mammary cells infected with miR - 150.

While found in some mammary cells prior to pregnancy, the activated form of STAT5 is detected in the great majority of epithelial mammary cells, and at increased levels, during pregnancy and lactation (Liu et al., 1995; Wagner and Rui, 2008).

While vitamin A is best known for its vital role in vision, the retinoid forms of this vitamin also participate in physiological activities related to the immune system, inflammatory system, maintenance of epithelial and mucosal tissues, growth, reproduction, bone development, creation of red blood cells, and production of spermatozoa (male reproductive cells).

They also serve as the major energy source for colonocytes (epithelial cells of the colon) and are thought to regulate human gene expression in order to reduce the risk of gastrointestinal disorders, some forms of cancer, and cardiovascular disease.

There are various types of bladder tumors like squamous cell carcinoma (arise in the epithelial cells), adenocarcinoma (arise in the glandular epithelium), undifferentiated carcinoma, rhabdomyosarcoma (tumor of the striated muscle - form of fibers combined into parallel fibers like the skeletal and the cardiac muscles), fibroma (tumors made of fibrous or connective tissue.