Sentences with phrase «epithelial tubes»

Leveraging the phylogenetic position of Cnidaria and the accessibility of Nematostella tentacle tubes to optical observation and experimental manipulation (see Video 2), we will define the biochemical and mechanical cues that drive the morphogenesis of epithelial tubes in a broad evolutionary context.

It may also represent a universal mechanism that regulates contractility in other epithelial tubes, including those found throughout our bodies.

Defects in the architecture of epithelial tubes lead to diseases such as cholestasis, atherosclerosis and polycystic kidney disease.

The elegant feedback system discovered in this study links the regulation of contraction to the shape and function of epithelial tubes via mechanical and biochemical signalling.

Our blood vessels, kidneys and pancreas, mammary, salivary and tear glands, are all essentially composed of epithelial tubes.

With each breath, for example, epithelial tubes transport oxygen to the lungs.

This contraction is similar to that observed in other epithelial tubes.

Researchers at the Mechanobiology Institute (MBI), National University of Singapore (NUS) have identified a novel mechanosensitive regulation of epithelial tube contraction.

Problems in epithelial tube contractility are responsible for asthma, raised blood pressure and gastrointestinal disorders.

MBI scientists have discovered a feedback mechanism that regulates epithelial tube contractility in a living organism, the C. elegans nematode worm.

The similarities led MBI Principal Investigator, Associate Professor Ronen Zaidel - Bar and graduate student Ms Tan Pei Yi to use the spermatheca as a model to study epithelial tube contraction.

Not exact matches

The tubes enclose hollow spaces called lumens and are primarily composed of a single or multiple layers of epithelial cells.

As an important prerequisite for tube formation, epithelial cells become asymmetric or «polar», acquiring structurally and functionally distinct ends or surfaces.

Spira hopes ultimately to develop a less invasive test using throat epithelial cells, which are easier to access than bronchial tube cells.

In search of early markers of lung cancer, pulmonary and critical care physicians Avrum Spira and Jerome Brody of the Boston Medical Center sampled bronchial tube epithelial cells from 85 people.

In that randomized, double - blind, placebo - controlled, phase III trial, 561 patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who were in complete or partial response to platinum - based chemotherapy were treated with either rucaparib 600 mg orally twice daily (372 patients) or to placebo (189 patients).

We have recently shown that in avian embryos, muscle formation is initiated by Delta1 - positive neural crest cells migrating from the dorsal neural tube that, in passing, trigger NOTCH signalling and myogenesis in selected epithelial somite progenitor cells, allowing them to migrate into the nascent muscle to differentiate.

ZEJULA is the first and only once - daily PARP inhibitor for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum - based chemotherapy.1 - 3

ZEJULA is indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum - based chemotherapy.

Nematostella has both extreme regenerative capacities and highly manipulable development, and we will capitalise on this rare combination of traits to identify the mechanisms that restore epithelial tentacle tubes after amputation.

FORWARD1: A Randomized, Open Label Phase 3 Study to Evaluate the Safety and Efficacy of Mirvetuximab Soravtansine (IMGN853) Versus Investigator's Choice of Chemotherapy in Women with Folate Receptor Alpha - Positive Advanced Epithelial Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer

The FDA has granted approval of rucaparib for maintenance therapy in patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer.

Dog's urine normally contains a trace amount of protein in the urine, as proteins are blocked by the glomerulus, the part of the kidney that filters waste products, or pass through the glomerulus and then reabsorbed by renal tubes or broken down by the epithelial cells of the renal tubes.

Epidermoid and dermoid cysts result from inclusion of epithelial components of embryonal tissue at the time of closure of the neural tube.