Not exact matches
The retinal pigment
epithelium (RPE) is a single layer of
cells that accomplishes multiple
functions, such as providing survival molecules that prevent photoreceptors from dying.
Although this human Gut Chip recreated the villus
epithelium of normal intestine and enabled new insights into how flow and cyclic peristalsis affects intestinal differentiation and
function, it could not be used to study processes that relied on normal intestinal
cells from individual donors, which, for example, is crucial for studying patient - specific responses for personalized medicine.
The researchers analyzed the exposed
cells to determine the effects of fungal exposure on permeability properties and barrier
function of the
epithelium.
The other one, the finding by the Clevers group in Utrecht that adult Lgr5 + stem
cells from the intestine, grown 3D in the presence of basement membrane matrix and a defined set of niche factors, can develop into ever - expanding, genome - stable 3D organoids that resemble the structure and
function of the original intestinal
epithelium (13 - 16).
With age, our eyes accumulate waste in retinal pigment
epithelium (RPE), which supports the life and
function of photoreceptors (light sensitive
cells in the eye); in advanced stages, RPE and photoreceptors die.
The retinal pigment
epithelium (RPE) is a monolayer of
cells, residing at the back of the eye between Bruch's membrane and the retina, which is essential for photoreceptor
function and survival.
It is also required for the production and
function of immune
cells, which are needed for those occasions when the
epithelia is broken, in order to protect against bacteria, virus or fungi.