CD8 T cells specific for the noninflationary M45
epitope displayed a classic central memory phenotype, re-expressing the lymph node homing receptor CD62L and homeostatic cytokine receptors for IL - 7 and IL - 15, and produced low levels of IL - 2.
In a new study, researchers have discovered that around one third of all
the epitopes displayed for scanning by the immune system are a type known as «spliced» epitopes.
Not exact matches
Epitopes are
displayed on the surface of circulating immune cells and are where T cells bind antigens to fuel the immune response.
Unexpectedly,
epitope encoding regions were enriched for sites
displaying weak evidence of directional selection influenced by HIV - 1.