Sentences with phrase «erythroid cells»
Porphyrin formation entails PBG deaminase - dependent HMB synthesis; limiting (or absent) expression of downstream enzymes in the heme biosynthesis pathway (grey) leads to non-enzymatic cyclization of HMB to form uroporphyrinogen I, as in the erythroid cells of CEP patients (Discussion).
https://elifesciences.org/
The proteins in them are characteristic of fetal and embryonic cells rather than of mature erythrocytes, and the authors take care to call them «erythroid cells» rather than true erythrocytes.
Not exact matches
Cell culture steps were used by both groups to let cells recover after thawing and / or electroporation, and additionally to generate erythroid progenitor cells from edited CD34 + cells [1].
High level erythroid lineage - directed gene expression using globin gene regulatory elements following lentiviral vector mediated gene transfer into primitive human and murine hematopoietic cells.
It was heterozygous in most patients, homozygous in a subset as a result of mitotic recombination, and arose in a multipotent progenitor capable of giving rise to erythroid and myeloid cells.
Therapeutic levels of fetal hemoglobin in erythroid progeny of -LCB- beta -RCB-- thalassemic CD34 + cells following lentiviral vector - mediated gene transfer.
Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation.