A recent review from Juliana Xavier ‐ Ferrucio and Diane S. Krause (Yale University, New Haven, CT, USA) focuses on recent advances in the identification and characterization of bipotent megakaryocytic ‐
erythroid progenitors (MEPs).
Human erythropoiesis is a complex multistep process that involves the differentiation of early
erythroid progenitors to mature erythrocytes.
Cell culture steps were used by both groups to let cells recover after thawing and / or electroporation, and additionally to generate
erythroid progenitor cells from edited CD34 + cells [1].
Dual actions of Meis1 inhibit
erythroid progenitor development and sustain general hematopoietic cell proliferation.
Not exact matches
It was heterozygous in most patients, homozygous in a subset as a result of mitotic recombination, and arose in a multipotent
progenitor capable of giving rise to
erythroid and myeloid cells.