While I can understand that building upon the existing plot of Legacy of Kain could be nigh impossible,
especially when trying to bring new fans to the series — the ending of Defiance would give them a fairly clean slate to build a new plot without
referencing the past too much — perhaps a bit of fan - service here or there, or an
odd remark — but generally, it wouldn't be too much work to take the existing world and make something fresh.