Excess exogenous testosterone is converted to
estrogen by the enzyme aromatase.
Stinging nettle root extract can rectify this by inhibiting the process of aromatization (conversion of testosterone to
estrogen by enzyme aromatase).
Not exact matches
Though it's unclear what effect, if any, BPA may have on egg quality during IVF, «there is mounting data that a key
enzyme that helps convert testosterone to
estrogen may be inhibited
by BPA,» said Bloom.
Estrogen and the
enzyme COX - 2 have more in common than their ability to spark enthusiasm tainted
by controversy.
Researchers have linked increased resistance to bacterial pneumonia in female mice to an
enzyme activated
by the female sex hormone
estrogen.
By blocking the function of this
enzyme, Grecunin helps your body maintain high testosterone levels, and diminishes the effect of
estrogen.
Saw Palmetto works
by inhibiting the
enzyme that converts testosterone into dihydro - testosterone (DHT) and also blocks
estrogen at its receptors.
By reducing the pH in your colon, butyrate helps to inactivate these
estrogen reactivating
enzymes.
Studies show that nettle extracts do boost testosterone levels
by inhibiting the action of
enzyme aromatase that converts free testosterone to
estrogen as well as binding with the Sex hormone binding globulin that arrests free testosterone.
Cytochrome P450 (CYP)
enzymes well known for their involvement in the metabolism of tobacco carcinogens are also involved in
estrogen metabolism, and many are regulated
by estrogens (e.g. CYP 1A1, CYP 1B1, CYP 17) 5354, CYP 1B1, in particular, is upregulated
by equilin and equilinin (hormones from pregnant mares found in Premarin ®) which converts these
estrogens to 4 - OH (pro-carcinogenic) metabolites.
Urinary
estrogen levels outside the reference range may also be suggestive of intestinal dysbiosis since beta - glucuronidase
enzymes, which are produced
by E. coli, Clostridum and Bacteroides in the intestines, can de-conjugate conjugated
estrogens, enabling their return to the circulation.12 For these reasons, interventions that improve liver and gut function may assist in gradual normalization of
estrogen levels.
Oral supplementation with calcium - D - glucarate has been shown to inhibit beta - glucuronidase, an
enzyme produced
by colonic microflora (e.g., E.coli) that is capable of hydrolyzing glucuronide conjugates, thus returning
estrogen readied for excretion back into circulation.
Supplementation with Calcium D - glucarate supports proper elimination of
estrogen by inhibiting beta - glucuronidase, an
enzyme produced
by colonic microflora (e.g., E.coli) that hydrolyzes glucuronide conjugates, thus returning
estrogen into circulation.
In addition, conjugated
estrogens can be re-activated in the intestines and returned to circulation via the action of beta - glucuronidase
enzymes, which are produced
by E. coli, Clostridum and Bacteroides 13; thus intestinal dysbiosis may increase a man's circulating levels of active
estrogens).
In addition, conjugated
estrogens can be re-activated in the intestines and returned to circulation via the action of beta - glucuronidase
enzymes, which are produced
by E. coli, Clostridum and Bacteroides12, thus intestinal dysbiosis may increase circulating levels of active
estrogens).
Fenugreek increases testosterone indirectly
by lowering the quantity of
enzymes that convert testosterone into
estrogen.
Even with ovaries removed, women make
estrogen, primarily
by an aromatase
enzyme in body fat and breasts that converts an adrenal hormone, androstenedione, into estrone.
Some vegetables may inhibit aromatase, the
enzyme used
by breast cancer tumors to produce their own
estrogen.
In the early 1980's it was found to have the ability to inhibit the conversion of testosterone into
estrogens by inhibiting the
enzyme called aromatase.
High insulin or insulin resistance from blood sugar imbalance also contributes to
estrogen dominance
by increasing the activity of an
enzyme call aromatase, which is linked to the production of
estrogen
Similarly to their
estrogen lowering effects
by inhibiting the aromatase
enzyme, both progesterone and Vitamin E also work
by directly blocking
estrogen receptors.
For example, what if spearmint tea works
by increasing the aromatase
enzyme, the
enzyme which creates
estrogen via conversion from testosterone, and thus increases overall
estrogen levels too?
DIM is not an
estrogen or a hormone, but like
estrogen DIM can be metabolized only
by a special class of cytochrome
enzymes that reside in cell membranes in the non-water part of cells.
The reason:
By blocking the 5 - alpha reductase enzyme they're actually giving free rein to another substance called aromatase — an enzyme in your body that, when left alone, wreaks absolute havoc in your body by converting testosterone into estradiol — the most powerful form of estroge
By blocking the 5 - alpha reductase
enzyme they're actually giving free rein to another substance called aromatase — an
enzyme in your body that, when left alone, wreaks absolute havoc in your body
by converting testosterone into estradiol — the most powerful form of estroge
by converting testosterone into estradiol — the most powerful form of
estrogen!
Part of the mechanism is
by androgenic interference with the
estrogen receptor (ER) and lowering circulating
estrogen levels
by competitively inhibiting the aromatase
enzyme.