Sentences with phrase «estrogen effects on»

Functional magnetic resonance imaging and estrogen effects on the brain: cautious interpretation of a BOLD finding

Therefore, the mechanism proposed behind decreased female central insulin sensitivity is a modulation caused by brain estrogen signaling, potentially mediated by estrogen effects on ERα in various regions of the hypothalamus.

For severe cases, doctors sometimes prescribe Danazol, a steroid derivative that decreases levels of the reproductive hormones FSH and LH, or tamoxifen, a breast - cancer drug that helps relieve breast pain by blocking estrogen receptors, thus preventing estrogens effect on breast tissue.

Not exact matches

Scientific research has also questioned the potential health effects of a regular soy - based diet on infants due to its estrogen - like effects.

Though it's unclear what effect, if any, BPA may have on egg quality during IVF, «there is mounting data that a key enzyme that helps convert testosterone to estrogen may be inhibited by BPA,» said Bloom.

Estrogen is thought to be protective of heart health through its beneficial effects on cholesterol and because it increases the flexibility of blood vessels and arteries, allowing them to accommodate blood flow.

No one has yet studied the effects of estrogen on wild songbird populations.»

She has described the impact that different estrogen receptors have on breast, pancreatic, and colorectal cancer, including transcriptomic effects involving long noncoding RNAs and microRNAs.

However, Speroni and colleagues found that BPA did not have the same effect on the mouse mammary bud as did estrogen, which inhibited mammary gland growth.

Ana Soto, professor of cellular biology at Tufts University School of Medicine, and her colleagues were studying the effects of estrogen on a breast cancer cell line.

This National Institutes of Health - funded study examined the effect of estrogen replacement on mental processes, including memory, in 29 amenorrheic female athletes ages 14 to 25 years compared to 19 who received no estrogen replacement.

Estrogen is a tiny molecule, but it can have big effects on humans and other animals.

... Larger studies with hormonal assessments and long - term follow - up are needed to better understand the effect of concussion on the HPO axis and potential implications for menstrual patterns, estrogen production and any persistent consequences,» the article concludes.

«A number of scientists are working on the effect of estrogens on pancreatic insulin - producing cells,» says Sandra Handgraaf, a researcher at the Faculty of Medicine and the first author of this work.

New findings suggest that taking estrogen has no effect on brain performance, no matter how early or late women start taking it

In addition to 6 - PN, Bolton and her colleagues studied 8 - prenylnarigenin (8 - PN), isoxanthohumol (IX) and xanthohumol (XH) for their effects on estrogen metabolism in breast cells.

But she notes that progestin is thought to counteract the effects of estrogen on brain tissue and that estrogen taken by itself may yet be good for the brain.

Some examples of the scholars» projects are: effects of estrogen on cardiac fibrosis after myocardial infarction, depression and the growth - hormone axis, substance abuse, stress and nicotine, cardiovascular risk in spinal cord injury, and pharmacogenomics and the treatment of breast cancer in elderly women.

The reward center of the brain is much more attuned to the pleasurable effects of alcohol when estrogen levels are elevated, an effect that may underlie the development of addiction in women, according to a study on mice at the University of Illinois at Chicago.

Previous studies of postmenopausal women have suggested the beneficial effect of estrogen therapy on muscle mass and function.

Some researchers have speculated that the effect of estrogen on cognitive aging might differ depending on when exposure occurs.

This structurally unique ligand turns on the body's estrogen receptors without the negative effects of excessive estrogen.

Their study, conducted in 400 healthy men ages 20 to 50, found that higher levels of testosterone led to lower levels of HDL cholesterol, or «good» cholesterol, but estrogen appeared to have no effect on HDL cholesterol.

To measure the effect of estrogen therapy on working memory under stress, Ycaza Herrera recruited 42 women with an average age of 66 from the USC Early versus Late Intervention Trial with Estradiol led by Howard Hodis, a professor at the Keck School of Medicine of USC and a coauthor of the new study.

Gwendolyn Thomas, assistant professor of exercise science, is the co-author of a groundbreaking article in the Obesity Journal (The Obesity Society, 2017) about the effects of exercise and physical activity on postmenopausal breast cancer survivors taking AIs — hormone - therapy drugs that stop the production of estrogen.

The first estrogen bioassay, (a bioassay is a measurement of the potency of a substance by its effect on living cells or tissues), is developed for use in pharmaceutical research.

«Our data further suggest that, despite the historical bias toward the effects of estrogen on the estrogen receptor, it's the progesterone receptor that dominantly controls estrogen receptor activity when both receptors are present and activated.»

Effect of 17β - estradiol and flavonoids on the regulation of expression of newly identified estrogen responsive genes in a rat raphe nuclei - derived cell line.

Hyperglycemia inhibits antiproliferative effects of estrogen on vascular smooth muscle cells.

The effects of androgens and estrogens on preadipocyte proliferation in human adipose tissue: influence of gender and site

Moreover, estrogen can exert direct effects on fat tissue by enhancing proliferation of preadipocytes, especially in females (232), and by up - regulating sc α2A - adrenergic receptors promoting SAT accumulation, notably in premenopausal women (233).

Across the cycle, estrogens may increase ACTH release and corticosterone levels, related to estrogen levels, whereas androgens exerted an inhibitory effect on the HPA axis stress response (245).

No noteworthy interactions with age, race / ethnicity, body mass index, prior hormone use, smoking status, blood pressure, diabetes, aspirin use, or statin use were found for the effect of estrogen plus progestin on CHD, stroke, or VTE.

Babajko reported that an increase in estrogen activity had a greater effect on the tooth enamel in male rats than in female rats.

Rapid effects of estrogens on visual processing in male goldfish, Carassius auratus.

Nicole Sekula: Rapid effects of estrogens on visual processing in male Carassius auratus (Advisor: R. Thompson)

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) tranEstrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) tranestrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

We are currently trying to identify the membrane receptors that mediate rapid effects of androgens and estrogens on behavioral and physiological processes related to courtship in goldfish, as well as to determine if these steroids rapidly affect early stages of sensory processing in ways that amplify neural responses to social stimuli.

We're going to focus on six hormones that have the profoundest effect in this respect: insulin, testosterone, estrogen, cortisol, human growth hormone and the thyroid hormones.

Green tea has a significant effect on estrogen because of one component called «sex hormone binding globulin» (SHBG) found in the tea.

Because estrogen may be linked to bone density, a woman who isn't having a regular period may not be benefiting from the hormone's protective effects on bone health, Dr. Adimoolam explains.

Previous studies have linked certain chemicals to disruptions in the reproductive hormones, including estrogen, which can then have unhealthy effects on the heart and bone.

The bad: When you lose estrogen, you lose its protective effects on your heart and bones, so your risk of osteoporosis and heart disease rises.

Estrogen and progesterone affect our brain chemistry, so different pills with different doses can have changing effects on our brain and moods.

«Obesity may... promote estrogen production and breast cell proliferation, in addition to the direct effect alcohol can have on estrogen metabolism and levels in the body,» she explains.

«Whether you're nursing or perimenopausal or menopausal, a lack of estrogen has a direct effect on your vaginal tissue,» explains Dr. Dweck.

The cancer promoting effects of estrogen on breast tissue are restricted by lignan compounds which bind to estrogen receptors.

Your body has to maintain a delicate balance of hormones at the right time, and when estrogen is at the optimal level, it has a calming effect on the brain.

Although estrogen, a key component in most forms of hormonal birth control, doesn't directly cause weight gain, it might be the reason a woman doesn't feel as full after she eats — thanks to estrogen's effect on hormones that affect appetite, explains nutritionist Alisa Vitti, founder of FLOliving.com.

Turmeric not only tackles the environmental cause of man boobs by blocking the effects of estrogen on a cellular level, and helping to boost testosterone, but it also has a big impact on your genes.