Ana Soto, professor of cellular biology at Tufts University School of Medicine, and her colleagues were studying the effects of
estrogen on a breast cancer cell line.
(18) http://jama.ama-assn.org/cgi/content/full/295/14/1647 Effects of Conjugated Equine
Estrogens on Breast Cancer and Mammography Screening in Postmenopausal Women With Hysterectomy.
Not exact matches
Bloch's colleagues at the National Institute of Environmental Health Sciences tested the oils in gene expression studies
on lab - grown human
breast cancer cells and found that they could mimic
estrogens, the primary female sex hormones, and inhibit androgens, the primary male sex hormones.
She has described the impact that different
estrogen receptors have
on breast, pancreatic, and colorectal
cancer, including transcriptomic effects involving long noncoding RNAs and microRNAs.
For this study, Dr. Lou and his colleagues focused
on triple - negative
breast cancer, which is difficult to treat, because it does not exhibit receptors for
estrogen, progesterone or the HER - 2 / neu gene, which are targets for many current
breast cancer treatments.
Triple - negative
breast cancers are those whose cells lack
estrogen receptors and progesterone receptors, and do not have an excess of the HER2 protein
on their surfaces.
Some examples of the scholars» projects are: effects of
estrogen on cardiac fibrosis after myocardial infarction, depression and the growth - hormone axis, substance abuse, stress and nicotine, cardiovascular risk in spinal cord injury, and pharmacogenomics and the treatment of
breast cancer in elderly women.
Some women with
estrogen receptor - positive
breast cancer do extremely well
on such anti-hormone treatment.
Triple negative
breast cancers are those that do not have
estrogen or progesterone receptors, and do not have an excess of the HER2 protein
on the
cancer cell surfaces.
Because most
breast cancers are hormone receptor - positive (i.e., they use
estrogen or progesterone to grow and spread), survivors often rely
on hormone therapy, such as AIs, to keep the disease from returning.
Gwendolyn Thomas, assistant professor of exercise science, is the co-author of a groundbreaking article in the Obesity Journal (The Obesity Society, 2017) about the effects of exercise and physical activity
on postmenopausal
breast cancer survivors taking AIs — hormone - therapy drugs that stop the production of
estrogen.
Depending
on characteristics such as how many tumor cells, blood vessel cells, and immune cells are touching each other, the tumor microenvironment can nearly triple the chance that a common type of
breast cancer (
estrogen - receptor positive / HER2 negative) that has reached the lymph nodes will also metastasize, Condeelis and colleagues showed in a 2014 study of 3,760 patients.
«The treatment for
breast cancer is currently dependent
on the type of
breast cancer, defined by the
estrogen receptor, progesterone receptor, and HER2 status.
He is currently writing for
breast cancer survivors and their oncologists about the important role that
estrogens and antiestrogens have in the brain,
on cognitive function, and
on mental health.
Potential cardioprotection was based
on generally supportive data
on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either
estrogen alone or, less frequently, combined
estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive
breast cancer was designated as a primary adverse outcome based
on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other
cancers; and other fractures.3, 6,9
Common variants
on chromosomes 2q35 and 16q12 confer susceptibility to
estrogen receptor - positive
breast cancer.
Common variants
on chromosone 5p12 confer susceptibility to
estrogen receptor - positive
breast cancer.
For severe cases, doctors sometimes prescribe Danazol, a steroid derivative that decreases levels of the reproductive hormones FSH and LH, or tamoxifen, a
breast -
cancer drug that helps relieve
breast pain by blocking
estrogen receptors, thus preventing
estrogens effect
on breast tissue.
The
cancer promoting effects of
estrogen on breast tissue are restricted by lignan compounds which bind to
estrogen receptors.
Your treatment will depend
on where your
cancer started, whether it has invaded other
breast tissue or spread to other parts of your body, and whether hormones like
estrogen or progesterone fuel its growth, among other factors.
«In the Womens Health Initiative (WHI) trial, when women got seven years of
estrogen alone, there was no increased risk of
breast cancer, but after four to five years
on combined hormone therapy, the risk emerges,» she says.
Now, a study published in the August 2014 issue of
Cancer Research states that women taking birth control pills are at higher risk for breast cancer, and that the risk depends on the amount of estrogen in that particular
Cancer Research states that women taking birth control pills are at higher risk for
breast cancer, and that the risk depends on the amount of estrogen in that particular
cancer, and that the risk depends
on the amount of
estrogen in that particular pill.
In fact, over time,
estrogen plus progestin can raise a womans risk for
breast cancer by 24 %; even if you take
estrogen on its own for more than 10 to 15 years, your risk may still go up.
active ingredient in antiperspirants, all natural deodorant, aluminum based compounds and parabans, baby was nursing, benefits of coconut oil, chemicals entering her body, coconut oil is great to cook with, coconut oil to cook, connection between underam antiperspirants or deodorants and
breast cancer, cooking with coconut oil is much healthier than olive oil, deodorant breastfeeding, developement of
breast cancer,
estrogen has ability to promote growth of
breast cancer cells, homemade deodorant, ingredients in deodorants and antiperspirants, Mommy Footprint fan page, sticking
on stainless steel pans, stop using deodorant, tandem nursing twins, traditional deodorant, women and men sweat and react to deodorants differently
Vaginal
estrogen therapy may also be used in women who have
breast, cervical or ovarian
cancer, and medical consultation must be sought for proper advice
on its risks and benefits.
Generally, I start women
on 75 mg DIM, twice a day, unless they have a history of
estrogen - dependent health issues such as
breast or uterine
cancer, fibroid formation, or cyst formation, in which case, I recommend 150 mg, twice a day.
It goes into great detail
on explaining hormones,
estrogen's role in the
cancer process, how chemicals and toxins in our environment contribute to the increase of
breast cancer, what role the liver plays in detoxifying our body and how we can support the liver.
Studies have shown that women
on a high - fiber diet have lower levels of circulating
estrogen, meaning less
estrogen stimulation of
breast tissue, for example, which reduces the risk of
breast cancer.
Given the existence of (weak) evidence that postmenopausal therapy with oral
estrogen may increases
breast cancer risk, it is recommended that women at risk of, or who already have been diagnosed with
breast cancer, should avoid soy products just to be
on the safe side.
On top of all the nasty symptoms and a blocked metabolism, if not properly balanced out,
estrogen dominance may lead to endometriosis, fibroids, hormone - related
cancers (such as
breast cancer), and metabolic syndrome.
From my viewing of the videos, I think you may find the best information in his video
on Breast Cancer and Flaxseeds as a way of learning how certain plant based foods (especially flax) «block»
estrogen receptors (there are alpha and beta receptors, Dr. G does an elegant job of explaining the differences).
Despite decades of research clearly showing that HRT significantly increases
breast cancer, millions of women worldwide are
on unopposed
estrogen for treatment of menopausal symptoms.
More
on Breast Cancer and Hormone Levels If high estrogen levels were the primary cause of breast cancer, we would expect to find more breast cancer mortality in women with higher hormone levels at age 30, and less breast cancer in women with low hormone levels at age 60 (post-menopa
Breast Cancer and Hormone Levels If high estrogen levels were the primary cause of breast cancer, we would expect to find more breast cancer mortality in women with higher hormone levels at age 30, and less breast cancer in women with low hormone levels at age 60 (post-menopa
Cancer and Hormone Levels If high
estrogen levels were the primary cause of
breast cancer, we would expect to find more breast cancer mortality in women with higher hormone levels at age 30, and less breast cancer in women with low hormone levels at age 60 (post-menopa
breast cancer, we would expect to find more breast cancer mortality in women with higher hormone levels at age 30, and less breast cancer in women with low hormone levels at age 60 (post-menopa
cancer, we would expect to find more
breast cancer mortality in women with higher hormone levels at age 30, and less breast cancer in women with low hormone levels at age 60 (post-menopa
breast cancer mortality in women with higher hormone levels at age 30, and less breast cancer in women with low hormone levels at age 60 (post-menopa
cancer mortality in women with higher hormone levels at age 30, and less
breast cancer in women with low hormone levels at age 60 (post-menopa
breast cancer in women with low hormone levels at age 60 (post-menopa
cancer in women with low hormone levels at age 60 (post-menopausal).
Please note that many women are not familiar with the red flags of
estrogen dominance symptoms; they deserve special attention in relation to
breast cancer; they are shown in bold
on this list.
However, storm clouds soon appeared
on the horizon when four large scale studies showed increased
breast cancer and heart disease from this
estrogen - progestin combination pill.
Dr. Lindsey Berkson: One of my specialties is
breast cancer because DES daughters, Dartmouth proved this with a longitudinal trial and the scientist who was the head of that was kind of enough to give me a really beautiful comment
on that book Safe Hormones, Smart Women, 85 % many women who were exposed to this powerful
estrogen in the womb got
breast cancer by age 45.
Dr. Lindsey Berkson: For example, like melatonin, we'll get a woman who just had
breast cancer on high dose melatonin because it down regulates
estrogen alpha receptors so that your... In fact, if you give a very high dose of melatonin to a young menstruating woman, you can get her to stop menstruating because it turns off
estrogen so powerfully.
Those are cells that were taken from nun many years ago that had
breast cancer and they propagated them and they do a lot of the research
on this line of cells that actually came from a nun that had
breast cancer called MCF - 7
estrogen dependent
breast cancer.
That's why the incidence of
breast cancer is going up in men when they're exposed to certain estrogenic chemicals
on the job, but also there can be epigenetic changes of the aromatase genes that make you more prone to not being able to do a good job of rinsing your hormones especially
estrogen out of your
breast.
A tissue culture study of human
breast -
cancer cells found that epigallocatechin gallate, or EGCG, an active compound in green tea, protects against some forms of
breast cancer by regulating
estrogen receptors
on breast cells and inhibiting growth and reproduction of
estrogen - dependant
breast -
cancer cells.
Studies have shown that stomach
cancer and
breast cancer are less common
on high - fiber diets.2, 3 Fiber affects levels of
estrogens in the body.
Effects of age,
breast density, ethnicity, and
estrogen replacement therapy
on screening mammographic sensitivity and
cancer stage at diagnosis: Review of 183,134 screening mammograms in Albuquerque, New Mexico.
The latest research
on natural progesterone and
breast cancer clearly indicates how important it is for women to maintain healthy, normal levels of progesterone that are in proper balance with
estrogen.
The beneficial effects of
estrogen on these discomforts are indisputable, but as women become more informed they see that the risks — especially of
breast cancer — may be too great to justify its use.
Estrogen is a prescription - only medication in the U.S., so you ll need to ask your doctor for a separate prescription for estrogen, preferably either estradiol, or a combination of estradiol and estriol, or estriol alone (please read our breast cancer book for details on using e
Estrogen is a prescription - only medication in the U.S., so you ll need to ask your doctor for a separate prescription for
estrogen, preferably either estradiol, or a combination of estradiol and estriol, or estriol alone (please read our breast cancer book for details on using e
estrogen, preferably either estradiol, or a combination of estradiol and estriol, or estriol alone (please read our
breast cancer book for details
on using estriol).
According to Lise Alschuler, author of the Definitive Guide To
Cancer: An Integrative Approach to Prevention, Treatment, and Healing, studies on flax lignans demonstrate safety and efficacy in their use against breast cancer, «inhibiting the growth of human estrogen - dependent breast cancer cells in mice and strengthening the tumor - inhibitory effect of tamoxifen&r
Cancer: An Integrative Approach to Prevention, Treatment, and Healing, studies
on flax lignans demonstrate safety and efficacy in their use against
breast cancer, «inhibiting the growth of human estrogen - dependent breast cancer cells in mice and strengthening the tumor - inhibitory effect of tamoxifen&r
cancer, «inhibiting the growth of human
estrogen - dependent
breast cancer cells in mice and strengthening the tumor - inhibitory effect of tamoxifen&r
cancer cells in mice and strengthening the tumor - inhibitory effect of tamoxifen».
For more
on breast cancer, see Relieving Yourself of Excess Estrogen; Flax and Fecal Flora; Broccoli Versus Breast Cancer Stem Cells, and all my other videos related to breast c
breast cancer, see Relieving Yourself of Excess Estrogen; Flax and Fecal Flora; Broccoli Versus Breast Cancer Stem Cells, and all my other videos related to breast c
cancer, see Relieving Yourself of Excess
Estrogen; Flax and Fecal Flora; Broccoli Versus
Breast Cancer Stem Cells, and all my other videos related to breast c
Breast Cancer Stem Cells, and all my other videos related to breast c
Cancer Stem Cells, and all my other videos related to
breast c
breast cancercancer.
For more
on breast cancer see Relieving Yourself of Excess Estrogen, Flax and Fecal Flora, Broccoli Versus Breast Cancer Stem Cells and 49 other videos that touch on breast c
breast cancer see Relieving Yourself of Excess Estrogen, Flax and Fecal Flora, Broccoli Versus Breast Cancer Stem Cells and 49 other videos that touch on breast c
cancer see Relieving Yourself of Excess
Estrogen, Flax and Fecal Flora, Broccoli Versus
Breast Cancer Stem Cells and 49 other videos that touch on breast c
Breast Cancer Stem Cells and 49 other videos that touch on breast c
Cancer Stem Cells and 49 other videos that touch
on breast c
breast cancercancer.
On the other hand, when too much
estrogen is around, rye's lignans, by occupying
estrogen receptors, block out the much more powerful human
estrogens, causing a lowering in estrogenic activity, and providing potential protection against
breast cancer.
Intervention Studies Most intervention studies
on fiber and
breast cancer have examined fiber intake and plasma or urinary indicators of
estrogen (e.g., estrone, estradiol).