Sentences with phrase «estrogen receptor alpha»

Sang - Hyuk Chung, 1 Kerri Weidmeyer, 1 Anna Shai, 1 Kenneth S. Korach, 2 and Paul F. Lambert 1, Requirement for Estrogen Receptor Alpha in a Mouse Model for Human Papillomavirus - Associate Cervice Cancer.

Characterization of the ovarian and reproductive abnormalities in prepubertal and adult estrogen non-responsive estrogen receptor alpha knock - in (ENERKI) mice.

Of these genes, nearly half that were being suppressed were regulated by estrogen receptor alpha (ESR1), and their down - regulation was noted by the 30 minute mark.

But as the cells become cancerous, the levels of estrogen receptor alpha crash to the point of being undetectable.»

, Phytoestrogenic activity of blackcurrant (Ribes nigrum) anthocyanins is mediated through estrogen receptor alpha, 2015

In addition, the tumor was positive for estrogen receptor alpha (ER alpha) and cell proliferation marker Ki67, and negative for receptor tyrosine kinase HER2 / ErbB2, suggesting that it has features like luminal B type breast cancer in humans.

Estrogen non-responsive estrogen receptor alpha (ERalpha) knock - in (ENERKI) mice have a mutation (glycine 525 to leucine, G525L) in the ligand - binding domain of ERalpha.

About 70 percent of breast cancer tumors are positive for a protein called «estrogen receptor alpha,» which prevents HOXC10 from killing the cancer.

They also show increased expression of the estrogen receptor alpha [ER +] gene that drives cell division,» says Koshy.

Sexual responses of the male rat medial preoptic area and medial amygdala to estrogen: site specific reduction of estrogen receptor alpha.

Dissection of the LXXLL nuclear receptor - coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta

Adequate levels of other estrogen estriol can reduce risk and improve symptoms of autoimmune diseases such as multiple sclerosis, rheumatoid arthritis and autoimmune thyroiditis because it stimulates an «estrogen receptor alpha».

Moreover, they have shown that, through differential patterns of DNA methylation of the promoter region and thereby differential expression of the estrogen receptor alpha gene in the medial preoptic area (MPOA) of the brain, this individual variation of early experience influences adult reproductive behaviour, suggesting a mechanism for intergenerational transmission of the pattern of maternal care [137, 138].