Sentences with phrase «estrogen receptor positive breast cancer»

Even if we take all of the women with estrogen receptor positive breast cancer, they are not all the same.
The study, published in the Journal of the National Cancer Institute (JNCI), identified four genes that are linked to tamoxifen resistance and poor prognosis of breast cancer, by comparing results obtained in a new animal model, in human breast cancer cells grown in culture, and in publically available datasets collected from thousands of estrogen receptor positive breast cancer patients treated with tamoxifen.
It was used in this study for the first time to study factors that cause estrogen receptor positive breast cancer to recur during tamoxifen therapy.
In addition, laboratory studies showed ICEC0942 worked better in combination with traditional hormone therapies for estrogen receptor positive breast cancer cells, which have not yet become resistant.
WASHINGTON (September 8, 2016)-- An animal study suggests that resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals.
In particular, KMT2C / MLL3, which is mutated in about 7 % of all estrogen receptor positive breast cancers, is a histone methyltransferase that creates the H3K4me1 mark at enhancers.
Excess estrogen is a problem for women predisposed to estrogen receptor positive breast cancers.
And apples seem to work best against estrogen receptor negative breast cancer, which is much harder to treat than estrogen receptor positive breast cancer.
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