To understand how
estrogen therapy works, we look at what happens when hormone production slows down.
Estrogen therapy works to restore a healthy supply of estrogen to the body.
Not exact matches
However, along with this seemingly linear storyline in which retinoids block progesterone's promotion of CK5 + cells, previous
work in the lab of CU Cancer Center investigator Peter Kabos, MD, and others shows that breast cancers treated with anti-
estrogen drugs like tamoxifen or aromatase inhibitors show an increased population of CK5 + cells — it is as if these
therapies remove the roadblock of
estrogen - dependent cells, leaving CK5 + cells to proliferate.
Since the report that it did cause breast cancer and many women have stopped taking hormone replacement
therapy, we've seen a decrease in breast - cancer incidence, exactly what you'd predict for our understanding of how
estrogens work.
«This could be very applicable for women suffering from hot flashes or depression for whom
estrogen therapy is really counter-indicated,» says neuropharmacologist Roberta Brinton of the University of Southern California in Los Angeles, who was not involved in the new
work.
To measure the effect of
estrogen therapy on
working memory under stress, Ycaza Herrera recruited 42 women with an average age of 66 from the USC Early versus Late Intervention Trial with Estradiol led by Howard Hodis, a professor at the Keck School of Medicine of USC and a coauthor of the new study.
By contrast, women receiving
estrogen therapy had a smaller increase in cortisol and showed no decrease in
working memory function.
Although bio-identical hormone
therapy seems to
work for most post-menopausal women for arthritis relief, there are a few women that still have arthritis and arthralgias in spite of the
estrogen cream.
Edit 2017: Recently, after learning about new research and
working with even more women, I'm finding that plant - based phytoestrogens may promote ER beta activity, which can lower estrogenic potency in the body as a whole, thereby decreasing the risk for certain cancers (this is not true of synthetic
estrogen, like that in hormonal birth control or
estrogen replacement
therapy).