Sentences with word «euchromatin»

A few months ago, research efforts led by Dr. Eran Meshorer (of Alexander Silberman Institute of Life Sciences at the Hebrew University) and Dr. Miguel Ramalho - Santos (of the University of California, San Francisco) published findings that suggest that Chd1 regulates euchromatin in mouse ESCs (Gaspar - Maia et al., 2009).

The goal of this collaboration is to produce a high - quality, publicly available sequence of Drosophila euchromatin by the end of this year.

However, when the histones are not bound to the DNA, the chromatin is extended (called euchromatin), and the DNA can be accessed and these genes can be expressed.

Specifically, they found that Chd1 is highly expressed in ESCs (relative to differentiated cells) and that Chd1 binds to the promoters of genes actively being transcribed in mouse ESC euchromatin.

It has three key protein domains: a DNA - binding domain, a chromodomain (which may bind euchromatin), and a helicase domain (which is thought to activate transcription by acting against repressing transcription effects, such as heterochromatin structure).

This computer rendering shows the skeletonized structure of heterochromatin (red represents a thin region while white represents a thick region), a tightly packed form of DNA, surrounding another form of DNA - carrying material known as euchromatin (dark blue represents a thin region and yellow represent the thickest) in a mouse's mature nerve cell.

Chd1 may function in ESCs to maintain chromatin in an open (euchromatin) state and potentially promote pluripotency in this way.

Currently, although it is known that Chd1 binds to euchromatin, the exact mechanisms of how Chd1 counters heterochromatin formation are unclear; it may act to prevent the spread of heterochromatin areas to euchromatin.

It was previously believed that embryonic stem cells had lots of open chromatin (euchromatin), but this was not a proven theory.

The view shown here slices from the surface of the nucleus through to its other side, and is color - coded for two types of genetic material: heterochromatin (blue) and euchromatin (green).

Regulatory elements tend to occur in regions of open chromatin (euchromatin), where they are accessible to transcription factors and other proteins.

Chromatin accessibility complex / ATP - utilizing chromatin assembly and remodeling factor help to establish basal transcriptional repression, conceivably through improving the regular spacing of nucleosomes in euchromatin.