Sentences with word «eukaryotic»

Eukaryotic refers to something that is related to or characteristic of eukaryotes. Full definition
Genome editing is used to make targeted modifications to the genome of eukaryotic cells.
Endosymbiotic theory, that attempts to explain the origins of eukaryotic cell organelles such as mitochondria in animals and fungi and chloroplasts in plants was greatly advanced by the seminal work of biologist Lynn Margulis in the 1960s.
But until now, prions were only seen in the cells of eukaryotic organisms, a group that includes animals, plants and fungi.
Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoires.
«Two of the three major processes in eukaryotic gene expression — splicing and translation — are now shown to be catalyzed by RNA,» said Jonathan Staley, PhD, associate professor of molecular genetics and cell biology at the University of Chicago and co-corresponding author on the study.
The research centered on eukaryotic initiation factor 2 alpha (eIF2alpha) and two enzymes that modify it with a phosphate group; this type of modification is termed phosphorylation.
A molecular evolutionary framework for eukaryotic model organisms.
However, it has long been known that regions of intrinsic disorder are comon in eukaryotic proteins.
Both the nucleus and the mitochondrion reflect a remarkable merger that took place early in eukaryotic life.
After a prolonged legal battle, USPTO in February ruled that it wasn't obvious that UC's discovery would work in human and other eukaryotic cells, giving the Broad a distinct patent advantage.
The team confirmed that guanabenz acts by temporarily blocking the reactivation of a protein known as eukaryotic translation initiation factor 2 (eIF2α).
As is often the case for yeast, the ability to sequence and analyze whole genomes at very deep coverage has yielded broad insights on eukaryotic genome evolution.
The ability to quickly obtain accurate genome sequences of eukaryotic pathogens at low costs provides a tremendous opportunity to identify novel targets for therapeutics, develop pesticides with increased target specificity and breed for resistance in food crops.
Currently I am involved in projects dealing with the prokaryotic ancestry of genomes of eukaryotic lineages.
The budding yeast, Saccharomyces cerevisiae, is a simple yet powerful eukaryotic model organism for aging research.
Bacterial signal transduction systems are capable of transmitting information from the exterior to a response using as few as two proteins whereas eukaryotic systems typically use multiple components.
Among our other collaborators are Rory Johnson (University of Bern), Rickard Sandberg, Magda Bienko, Nicola Crosetto (Karolinska Institutet) and the SciLifeLab Eukaryotic Single Cell Genomics facility.
Evolutionary questions (WP6) include the addition of uncultured lineages to retrieve a more complete eukaryotic Tree of Life, understanding the evolution of genes and pathways across different lineages, and population genomics in a given lineage or species group.
The Gordon and Betty Moore Foundation accepted sequencing nominations from Dr. Worden and provided sequencing funds in support of understanding eukaryotic algae.
We started with Xenopus rRNA because it was the first eukaryotic gene ever cloned.
In fact, as with eukaryotic organisms, division of Caulobacter cells generates two different daughter cells, which can be easily separated.
It reminded her of the proposed endosymbiotic theory, «of how mitochondria themselves (formerly free bacteria) got their start inside eukaryotic cells, possibly as a kind of limited parasite, then in the détente that followed, both cells found a way to share the food and contribute to each other's well - being.»
Case in point: in 1979, a year after Bob Swanson's pep talk to his Genentech biologists, a biologist then at Columbia University named Michael Wigler published a very clever method (called «co-transformation») for smuggling genes into eukaryotic cells; the university filed a patent application in 1980, with Wigler and two colleagues as inventors, and received the first of several patents in 1983.
Kim Orth of the University of Texas Southwestern Medical Center and the Howard Hughes Medical Institute has worked to elucidate the activity of bacterial virulence factors on the molecular level, providing insights into how bacteria cause disease and how eukaryotic host cells signalin response to infection.
We previously showed that the bacterial response regulator PhoB [14], [15] can be adapted to function in a partial synthetic eukaryotic signal transduction system [12].
The new arrangement, summarized in 2012 by Sina Adl of the University of Saskatchewan and colleagues in the Journal of Eukaryotic Microbiology, makes a fabulous mix of convergence and divergence.
The study provides new insights in how eukaryotic organisms gradually evolved from simpler microbial ancestors.
Our findings show that sex can generate phenotypic and genotypic diversity de novo in the pathogenic yeast C. neoformans with implications for other eukaryotic microbes and pathogens, including other fungi and parasites that are common pathogens of humans.
The sequencing project, which represented the first completely sequenced eukaryotic genome, culminated in the landmark publication «Life with 6000 Genes» (Goffeau et al. 1996).
Such series of cell fate transitions of stem cells ultimately lead to the development of a higher eukaryotic organism.
Excitingly, these proteins are functionally enriched for membrane bending, vesicular biogenesis, and trafficking activities, suggesting that eukaryotes evolved from an archaeal host that contained some key components that governed the emergence of eukaryotic cellular complexity after endosymbiosis.
Patent covers foundational CRISPR - Cas9 inventions for which Caribou holds an exclusive license from the University of California and the University of Vienna Claims cover CRISPR - Cas9 compositions for use in any non-cellular and cellular setting, including eukaryotic cells
The coherence of the NRY's gene content contrasts with the apparently haphazard content of most eukaryotic chromosomes.
Eukaryotic chromosomes contain both DNA and protein, tightly associated to form a substance called chromatin.
Ciliates are water - living unicellular eukaryotic organisms, characterized by the presence of hair - like organelles called cilia.
We have sequenced the genome of the endangered European eel using the MinION by Oxford Nanopore, and assembled these data using a novel algorithm specifically designed for large eukaryotic genomes.
Among other things, they discuss the evolution of life from its chemical precursors, the divergence of the fundamental groups of organisms, including eukaryotes (cells with nuclei) and prokaryotes (without nuclei), and the evolution of the main eukaryotic forms: plants, animals and fungi.
Recently, this very lab described the Asgard Archaea, an archaeal phylum with clear signs of cellular complexity, such as the presence of eukaryotic membrane trafficking components.
While directing an independent research program for almost two decades, Dr. Green was at the forefront of efforts to map, sequence, and understand eukaryotic genomes.
Principles for RNA metabolism and alternative transcription initiation within Read more about Principes of eukaryotic RNA metabolism -LSB-...]
In the mice with prion disease, Mallucci disrupted this process by neutralising the gene — called eukaryotic translation initiation factor, or eIF2alpha - P — that halts protein production.
Large multicellular eukaryotic organisms became common much later, about 600 million years ago, near the transition to the Phanerozoic Era, the «time of visible life.»
Our work focuses on two complementary aspects of genomics, (i) mechanisms of epigenetic regulation in eukaryotic chromatin and (ii) technologies of genetic engineering.
To enable such a system in plants, the re-designed receptors need to be targeted extracellularly and we need to address eukaryotic processes that are not fully understood, such as transmembrane signaling, signal - dependent nuclear translocation, and other signaling complexities.
The proto - eukaryote supposedly had all typical eukaryotic features but lacked mitochondria.
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