Our method, based ideally on 20x and 50x of NaS and Illumina reads respectively, provides an efficient and cost - effective way of sequencing microbial or small
eukaryotic genomes in a very short time even in small facilities.
Not exact matches
The EBP would focus on the natural world, providing a better understanding of biodiversity by first sequencing
in great detail the DNA of a member of each
eukaryotic family (about 9000
in all) and eventually generating coarser
genomes for the other eukaryotes.
Researchers from the University of Seville at the Andalusian Centre for Molecular Biology and Regenerative Medicine (Centro Andaluz de Biología Molecular y Medicina Regenerativa — Cabimer) have discovered that
in eukaryotic cells the proximity of the genes to the nuclear pores, which are found
in the nuclear membrane, contributes to maintaining the integrity of the
genome.
By using new methods to obtain
genome data from microbes that can not be grown
in the laboratory, we identified a new archaeal group that is related to the host cell from which
eukaryotic cells evolved.
We generate high - resolution 3D models of the spatial organization of the
genomes of distinct
eukaryotic cell types
in interphase to identify differences
in the chromatin landscape.
Strong functional patterns
in the evolution of
eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoires.
You are what you eat: a gene transfer ratchet could account for bacterial genes
in eukaryotic nuclear
genomes.
Nineteen laboratories
in Genome Science are designed to take students to a higher level of biological and technological integration — to study the function of
eukaryotic genes and
genomes.
We find homologs
in genomes across the
eukaryotic tree of life, map known and de novo protein functionalities, and examine co-evolution between proteins and protein motifs.
The team's work highlights this by presenting a comprehensive view of
genome evolution on many different levels (e.g., differences
in ploidy, aneuploidy, genetic variants, hybridization, and introgressions) that is difficult to obtain at the same scale and accuracy for other
eukaryotic organisms.
IRES was originally discovered
in poliovirus RNA, where it promotes translation of the viral
genome in eukaryotic cells.1, 2 Since then, a variety of IRES sequences have been discovered - many from viruses, but also some from cellular mRNAs.
The ability to quickly obtain accurate
genome sequences of
eukaryotic pathogens at low costs provides a tremendous opportunity to identify novel targets for therapeutics, develop pesticides with increased target specificity and breed for resistance
in food crops.
Eukaryotic genomes are non-randomly organized
in the nucleus.