Sentences with phrase «eukaryotic initiation»

They showed genetically that there was an additional response coming from the transcription factor — Forkhead box O (Foxo)-- which in turn enhances the transcription of one of the translational regulators: eukaryotic initiation factor 4E binding protein (4E - BP).

Eukaryotic Initiation Factor 4a3 is a selenium - regulated RNA - binding protein that selectively inhibits selenocysteine incorporation.

Here, we provide evidence that mTOR signaling phosphoproteins, including mTOR, eukaryotic initiation factor 4E — binding protein - 1, p70S6K, and ribosomal protein S6, are highly phosphorylated in ALK + ALCL cell lines and tumors.

The finding was a surprise because the protein is part of a larger assembly of proteins called eIF3 - eukaryotic initiation factor 3 — that has been known and studied for nearly 50 years, and no one suspected it's undercover role in the cell, Cate said.

Until now, this initiation protein was thought to be eIF4E (eukaryotic initiation factor 4E) for all mRNAs.

Not exact matches

Called eukaryotic translation initiation factor, or eIF2alpha - P, the gene generates a protein that needs to have a chemical grouping called a phosphate group attached to it to halt the protein production line.

The team confirmed that guanabenz acts by temporarily blocking the reactivation of a protein known as eukaryotic translation initiation factor 2 (eIF2α).

«These RNA molecules will fold into shapes that appear to mimic some of the initiation factors that that you would find in eukaryotic translation,» he says.

Principles for RNA metabolism and alternative transcription initiation within Read more about Principes of eukaryotic RNA metabolism -LSB-...]

For example, previous studies have shown that eukaryotic translation initiation factor (eIF4E) and cyclic AMP responsive element B (CREB) are known to be activated by radiation [37 - 40].

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA.

His basic research is focused on understanding how eukaryotic mRNAs recruit ribosomes, how ribosomes subsequently locate initiation codons, and how ribosomes regulate the translation of specific subsets of mRNAs.

mTORC1 is the central component of the insulin - signaling cascade [insulin / insulin - like growth factor (IGF)-- phosphatidylinositol 3 - kinase (PI3K) pathway)(Fig. 1) that regulates protein synthesis and mRNA translation through 2 primary mechanisms: 1) inactivation of the repressor of mRNA translation, eukaryotic translation initiation factor 4E - binding protein 1 (eIF4E - BP1), and 2) the activation of 70 - kDa ribosomal protein S6 kinase.