Sentences with phrase «eukaryotic translation initiation»

mTORC1 is the central component of the insulin - signaling cascade [insulin / insulin - like growth factor (IGF)-- phosphatidylinositol 3 - kinase (PI3K) pathway)(Fig. 1) that regulates protein synthesis and mRNA translation through 2 primary mechanisms: 1) inactivation of the repressor of mRNA translation, eukaryotic translation initiation factor 4E - binding protein 1 (eIF4E - BP1), and 2) the activation of 70 - kDa ribosomal protein S6 kinase.

For example, previous studies have shown that eukaryotic translation initiation factor (eIF4E) and cyclic AMP responsive element B (CREB) are known to be activated by radiation [37 - 40].

The team confirmed that guanabenz acts by temporarily blocking the reactivation of a protein known as eukaryotic translation initiation factor 2 (eIF2α).

Called eukaryotic translation initiation factor, or eIF2alpha - P, the gene generates a protein that needs to have a chemical grouping called a phosphate group attached to it to halt the protein production line.

Not exact matches

«These RNA molecules will fold into shapes that appear to mimic some of the initiation factors that that you would find in eukaryotic translation,» he says.

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA.

His basic research is focused on understanding how eukaryotic mRNAs recruit ribosomes, how ribosomes subsequently locate initiation codons, and how ribosomes regulate the translation of specific subsets of mRNAs.