Sentences with phrase «evade treatment»

Scientists at The Wistar Institute Melanoma Research Center have made huge strides in understanding the biology that underlies this disease, from basic genetics to the study of melanoma cell interaction with the microenvironment and new concepts that describe the stem cell - like abilities of melanoma to evade treatment.

Cancer researchers have applied a comprehensive set of analytical tools to lethal cases of metastatic prostate cancer, yielding a detailed map of the complex networks of interactions among genes and proteins that enable prostate cancer cells to proliferate and evade treatment.

The results, published in Nature Communications on Oct 30, highlight strategies to better evaluate drug effectiveness and inform the development of synergistic drug combinations to overcome the ability of tumors to evade treatment.

In addition, they could potentially make it possible to address a major obstacle to curing HIV: the virus's ability to establish a latent reservoir soon after infection, and so hide out in the body and evade treatment.

Microorganisms like bacteria and fungi can evade treatment by acquiring mutations in the genes targeted by antibiotics or antifungal drugs.

The findings, in mice and in human stomach cells, also raise questions about how cancer cells may evade treatment.

Timing may be decisive when it comes to overcoming cancer's ability to evade treatment.

«Studies like this also give us a better understanding of how cancer changes to evade treatments — knowledge we can use when we are designing the new cancer drugs of the future.»

Not exact matches

Last month the 32 - year - old Real Madrid striker became disgruntled as he felt singled out for disproportionate treatment by Spanish prosecutors, who accused him of evading tax of 14.7 million euros (# 12.8 m).

Based on the evolutionary idea that targeted epigenetic stochasticity can improve adaptation, these observations could explain how cancer cells are good at evading chemotherapy treatments and spreading from one part of the body to another, he adds.

«Ebola virus mutations may help it evade drug treatment.»

After treatment with AZA, the epigenetic changes were reversed, rendering the cancer cells unable to evade the immune system any longer.

Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body's immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.

Some scientists have blamed so - called cancer stem cells, a subset of cancer cells that might be able to remain dormant, evading chemotherapy or radiation treatments, only to form new tumors months or years later.

The report in PNAS said laboratory studies of how the virus evolves in response to exposure to neutralizing antibodies suggest that the MERS virus won't easily shape - shift to evade antibody treatments, as some viruses do.

Ollmann Saphire says the next step is to study how known mutations in Marburg evade such antibodies and to use that information to devise second - line treatments.

These patients were subsequently treated with the drug ketoconazole, which blocks the production of androgens outside of the testes (e.g., those developed by prostate cancer cells that are evading ADT treatment).

When the researchers tested the bNAbs as monotherapies, HIV levels typically decreased but rebounded within 2 weeks of stopping the treatment, as the virus mutated to evade the given antibody.

Researchers found that the drugs, called Hsp90 inhibitors, specifically target and inactivate a mechanism commonly used by prostate cancer cells to evade the effects of standard treatment.

Regardless of how immunotherapy could eventually influence cancer treatment, its development is a new revolution in cancer treatment, building on detailed biochemical knowledge of how cancer mutates and evades the immune response.

Drug resistant HIV can arise when HIV virus mutates to evade antiretroviral therapy (ART) drugs in infected people who have begun treatment.

Collectively, their work has elucidated foundational mechanisms in cancer's ability to evade immune recognition and, in doing so, has profoundly altered the understanding of disease development and treatment.

That it's possible for an author to evade vanity - press treatment through Tate is far less important than the probability that an author can evade vanity - press treatment through Tate.