Sentences with phrase «evaluate efficacy and safety»
U.S. Army Medical Research Institute of Infectious Diseases Viral Genomics Center, Frederick • MD 2009 — 2010 Microbiologist Collaborative part of multi-disciplinary team within highly - integrated environment to develop, optimize, characterize, and validate assays and sequencing methods in support of research projects aimed to identify threat agents and to evaluate efficacy and safety of vaccines and anti-viral therapies.
http://www.resumemycareer.com/
After all, the best way to help protect horses against EIV is to vaccinate before exposure to this highly contagious respiratory disease.8 And that's why horse owners can depend on the FLUVAC INNOVATOR vaccine line, because it helps offer demonstrated protection against EIV and is backed by the Zoetis commitment to continuously monitor and evaluate the efficacy and safety of its products.
Overall, SR - Tiget represents a multi-disciplinary research environment, which provides a unique blend of scientific expertise in the development of innovative gene and cell therapy strategies, access to relevant preclinical models to evaluate their efficacy and safety, as well as competence in conducting early phase clinical trials.
A Randomized, Phase III Trial to Evaluate The Efficacy and Safety of MK - 3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor - Negative Breast Cancer with ≥ 1 cm Residual Invasive Cancer or Positive Lymph Nodes (yPN +) After Neoadjuvant Chemotherapy
Dr. Timmerman, who holds the Effie Marie Cain Distinguished Chair in Cancer Therapy Research, has championed the use of SABR globally and has served as the lead investigator in several national trials designed to evaluate the efficacy and safety of SABR to treat cancer in the lung, liver, spine, and prostate.
The CO-STAR (Hepatitis C Patients on Opioid Substitution Therapy Antiviral Response) trial sought to evaluate the efficacy and safety of elbasvir - grazoprevir for injection drug users.
Further studies in animal models and patients (with altered TRPM7 channel function) have been initiated, in order to evaluate the efficacy and safety of magnesium as a therapeutic for this disease.
ObjectiveTo evaluate the efficacy and safety of magnesium sulfate in the resolution of vaginal bleeding and contractions in nonsevere placental abruption.
Detailed 48 - week results from a Phase 3 study evaluating the efficacy and safety of switching from a regimen containing abacavir, dolutegravir and lamivudine (600 / 50/300 mg)(ABC / DTG / 3TC) to Biktarvy, a once - daily single tablet regimen, in virologically suppressed adults with HIV.
In a study published online by JAMA Cardiology, Fredrik Björck, M.D., of Umea University, Umea, Sweden and colleagues evaluated the efficacy and safety of well - managed warfarin therapy in patients with nonvalvular atrial fibrillation.
The ENGOT - OV16 / NOVA trial evaluated the efficacy and safety of the PARP inhibitor niraparib as maintenance therapy in patients with recurrent ovarian cancer who respond to platinum - based chemotherapy.
The study evaluated the efficacy and safety of cabozantinib compared to placebo in 9 different solid tumor types including breast, lung, ovarian, and prostate.
Monies have gone to fund such projects as a postdoctoral fellow studying familial hypercholesterolemia, evaluating the efficacy and safety of a new drug for congenital hyperinsulinism, and identifying molecular targets for Pitt - Hopkins Syndrome treatments.
Not exact matches
Announced a clinical trial collaboration with Pfizer, Inc. (Pfizer) to evaluate the safety and efficacy of the investigational combination of Yescarta and Pfizer's utomilumab, a fully humanized 4 - 1BB agonist monoclonal antibody, in patients with refractory large B - cell lymphoma.
The new administration is taking shape and may potentially include an FDA commissioner who has argued the agency should consider safety when evaluating new drugs and devices and efficacy only after the drug has been legalized.
The aim of this trial is to evaluate the safety and efficacy of continuous KMC initiated immediately after birth compared to the current recommendation of initiating continuous KMC after stabilization, in improving survival of neonates with birth weight from 1.0 to < 1.8 kg.
Trials are currently underway to evaluate the safety and efficacy of antiretroviral regimens taken by the mother and / or infant after delivery to prevent transmission through breastfeeding.
Mumbengegwi takes these plants back to the lab to evaluate the efficacy, safety, and bioavailability of the various compounds.
In addition, the NFL should convene an independent committee of medical professionals, without ties to the NFL or any of its teams, to evaluate the safety and efficacy of the therapies, establishing a set of criteria for what is considered «safe» and «effective,» the authors said.
The FDA doesn't evaluate foods intended to aid general life conditions, such as mood and mental sharpness, so ginkgo biloba need not be certified for safety or efficacy.
Previous clinical trials have evaluated the efficacy, safety and tolerability of CIP on human patients.
Researchers conducted a double - blind, randomized, placebo - controlled clinical trial to evaluate the safety and efficacy of pinaverium.
The ADvance Trial, using a device from Functional Neuromodulation, Inc., is aimed at evaluating the safety, efficacy and tolerability of DBS in this patient population.
A clinical trial investigating a treatment for blindness is under way this winter to evaluate the safety and efficacy of replacing diseased eye cells with stem cells.
«The next steps are to develop tau - lowering therapeutics that could be used in humans and to evaluate their safety and efficacy in preclinical studies,» said Dr. Mucke, «objectives we are pursuing actively.»
The Phase 2/3 trials will be sponsored by Vtesse, a new biotech company that was formed specifically to evaluate the safety and efficacy of cyclodextrin for the treatment of NPC and ultimately obtain FDA labeling if the drug is effective.
This prospective, single - arm, phase II clinical trial was conducted to evaluate the safety, feasibility, and efficacy of induction chemotherapy followed by SABR in 34 patients who had biopsy - proven PDA.
He will continue evaluating the long - term safety and efficacy of Ins - PBA - F.
Since there is no vaccine or specific approved treatment for Ebola virus disease (EVD), there is a «moral obligation» to collect and share all data generated, to understand the safety and efficacy of any intervention, and to evaluate promising interventions to inform future research, says Dr. Eleanor Fish, the senior author and senior scientist in the Toronto General Hospital Research Institute (TGHRI).
As a first step in evaluating the safety and efficacy of the X4 - ZFNs in vivo, we employed a NSG humanized mouse model.
A Phase III, Open Label Study to Evaluate the Safety and Efficacy of INSTILADRIN (rAd - IFN / Syn3) Administered Intravesically to Patients with High Grade, BCG Unresponsive Non-Muscle Invasive Bladder Cancer
ViaCyte is proceeding to initiate an open - label clinical trial to evaluate the PEC - Direct product candidate for safety and definitive evidence of efficacy.
Dogs will be a crucial non clinical model to evaluate safety and efficacy of new therapeutics.
A Phase 1b / 2a Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of AMG 232 Combined with Trametinib and Dabrafenib or Trametinib in Adult Subjects with Metastatic Cutaneous Melanoma
SEATTLE, WA and DURHAM, NC — The HIV Vaccine Trials Network (HVTN) and the HIV Prevention Trials Network (HPTN) today announced the initiation of HVTN 704 / HPTN 085, also known as Antibody Mediated Prevention (AMP) or the AMP Study, a Phase 2b clinical trial to evaluate the safety and efficacy of VRC01, a broadly neutralizing monoclonal antibody (bnAb).
Finch expects to begin enrolling for a Phase II clinical trial to evaluate the safety and efficacy of FIN - 403 for the prevention of recurrence in recurrent C. difficile patients in the second half of 2017.
In Phase I clinical trials, patient safety and efficacy are evaluated.
Phase I / II Study to Evaluate the Safety, Efficacy, and Novel PET / CT Imaging Biomarkers of CB - 839 in Combination with Panitumumab and Irinotecan in Patients with Metastatic and Refractory RAS Wildtype Colorectal Cancer
The HVTN is an international collaboration that conducts all phases of clinical trials, from evaluating experimental vaccines for safety and the ability to stimulate immune responses, to testing vaccine efficacy.
The A4 study was designed to evaluate safety, tolerability and efficacy of Solanezumab in older individuals who have normal thinking and memory function but who may be at risk for developing dementia related to Alzheimer's disease (AD) in the future.
A Phase 2b Open - Label Extension Study to Evaluate the Long - term Safety and Efficacy of NEOD001 in Subjects with Light Chain (AL) Amyloidosis who were previously enrolled in Study NEOD001 - 201 (PRONTO)
«Since these molecules come from species other than humans, many studies must be done to evaluate their safety and efficacy in the context of treatment,» he says.
EOS100850 is currently being evaluated for safety and efficacy in preclinical models.
The funding will help support our current clinical trial evaluating the safety and efficacy of ViaCyte's PEC - Direct product candidate, which is in development as a potential cure for patients with high - risk type 1 diabetes.
It is currently being evaluated for safety and efficacy in preclinical models with a Phase I trial expected to begin in 2019.
The first - in - human STEP ONE * trial is evaluating the safety and efficacy of ViaCyte's PEC - Encap (a.k.a. VC - 01 ™) product candidate, a stem cell - derived, encapsulated cell replacement therapy.
The company's lead proprietary compound, LMTX ®, has recently completed three Phase 3 clinical trials to evaluate its safety and efficacy in the treatment of Alzheimer's disease and behavioural - variant frontotemporal dementia.
ViaCyte's VC - 01 ™ product candidate, a first - in - class cell replacement therapy for the treatment of type 1 diabetes, is currently being evaluated in a Phase 1/2 trial called STEP ONE, or Safety, Tolerability, and Efficacy of VC - 01 Combination Product in Type One Diabetes.
Paris, France, April 3, 2018, 5.35 pm CET — GenSight Biologics (Euronext: SIGHT, ISIN: FR0013183985, PEA - PME eligible), a biopharma company focused on discovering and developing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders, today announced topline results from the REVERSE Phase III clinical trial evaluating the safety and efficacy of a single intravitreal injection of GS010 (rAAV2 / 2 - ND 4) in 37 subjects whose visual loss due to 11778 - ND4 Leber Hereditary Optic Neuropathy (LHON) commenced between 6 and 12 months prior to study treatment.
REFLECT is a randomized, double - masked, placebo - controlled Phase III trial evaluating the safety and efficacy of bilateral injections of GS010 in patients with < 1 year of onset of vision loss in LHON.