Sentences with phrase «evaluate vaccine candidates»

We also work with partners to develop tools and processes to evaluate vaccine candidates.

Though a preventative vaccine for HIV does not yet exist, NIAID oversees a robust research program to develop and evaluate vaccine candidates.

Not exact matches

Based on their findings, they urge that «mosquito saliva and enhancing antibodies thus need to be considered when developing vaccines and drugs against dengue,» and specifically suggest that «animal models of dengue and pre-clinical validation of dengue vaccine candidates should be evaluated in the combined presence of mosquito saliva and enhancing antibodies.»

«HIV - 1 specific IgG3 is one biomarker that can be evaluated in further vaccine candidates.

The data obtained from this study provide a basis for more rapid, cost - effective clinical trials to evaluate new influenza drugs or to determine the efficacy of candidate vaccines for both seasonal and pandemic influenza.

NIBSC has a well - established, dedicated biological facility and relevant models for evaluating the protective potencies of BCG and new TB vaccine candidates.

In vitro reconstitution of B cell receptor - antigen interactions to evaluate potential vaccine candidates.

We will evaluate the immunogenicity of vaccine candidates (provided by user) administered by systemic, transdermal or mucosal routes and will monitor humoral responses and cellular responses.

In order to efficiently evaluate the newly designed vaccine candidates before testing them in clinical trials there is a need for development of reliable preclinical models.

As a site proposed for testing vaccines in humans, we requested and were given approval for evaluating different vaccine candidates for safety and effectiveness.

Four candidate vaccines for humans with or without alum adjuvant were evaluated in a mouse model of SARS, a VLP vaccine, the vaccine given to ferrets and NHP, another whole virus vaccine and an rDNA - produced S protein.

His lab has extensive experience evaluating and modulating T cell responses to tumors and viruses, including introducing genes into T cells to impart specificity and modulate function, designing strategies to overcome tolerance and enhance in vivo activity, and developing mouse models that more accurately model human immune responses to candidate vaccines.

Before joining IDRI, Tracey worked as a Protocol Development Manager with the HIV Vaccine Trials Network at the Fred Hutchinson Cancer Research Center where she led multi-disciplinary teams in the design and implementation of clinical trials evaluating candidate HIV and tuberculosis vaccines.

Portfolio management will be continued to evaluate and advise during the development process, and to prioritise vaccine candidates.

«This study allowed us to evaluate the protective efficacy of several prime - boost vaccine combinations, and these data will help guide the advancement of the most promising candidates into clinical trials,» noted lead author Dr. Dan Barouch of Beth Israel Deaconess Medical Center at Harvard Medical School and the Ragon Institute of MGH, MIT, and Harvard.

No such vaccine currently exists, and only a handful of the hundreds of potential candidates in the parasite genome have been evaluated.

The Bancroft laboratory was funded by TBVAC2020 to provide preclinical animal models to evaluate new TB vaccine candidates.

The Walter Reed Army Institute of Research (WRAIR) began vaccinations today in a Phase 1 clinical trial to evaluate the safety and immune response of a vaccine candidate to prevent Middle East... Read More