Sentences with phrase «evaluated in human patients»
This virus is currently being evaluated in human patients with liver cancer in an FDA - approved trial.
https://uwveterinarycare.wisc.edu/
Although this class of compounds has shown efficacy in a variety of cancers, interest in developing new topoisomerase I inhibitors, indenoisoquinolines, are currently being evaluated in human patients as agents with improved drug stability and measurable blood levels.
Not exact matches
No. 2: Alzheimer's disease treatment nets a breakthrough Roughly 99 % of all Alzheimer's drugs to enter human trials have ended up in the trash heap, but trials are under way evaluating drugs that could soon reshape patient treatment.
A clinical trial to evaluate whether the ointment can treat antibiotic resistant infections in human patients is scheduled for 2018.
«Data from this study serves as rationale to now include dogs with spontaneous cancers in the advancement and optimization of PMed for human patients,» according to the study, Prospective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating personalized medicine (PMed) trials.
The use of bone marrow - derived stem cells is well established in the treatment of human cancer patients, and veterinary applications for bone marrow - and adipose - derived stem cells are being evaluated.
«More research is needed to evaluate the efficacy of this use of a cancer medication to alleviate risk of sudden cardiac death, but we are hopeful that what we observed in mice will translate effectively to humans, providing patients and clinicians with a new paradigm for treating this common and life - threatening illness,» Dudley said.
Researchers at UCLA treat the first patients in the second FDA - approved study evaluating a therapy made from human embryonic stem cells.
Researchers have treated the first two patients in the second government - authorized attempt to evaluate a therapy created using human embryonic stem cells in the United States.
The researchers now plan to tweak the nanoparticles for direct use in human patients, working to evaluate the safety of the method prior to potential clinical trials.
• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study
To build upon the encouraging early discoveries, Helmsley renewed and expanded its Crohn's funding for the Institute in 2013 to begin new work with three major aims: 1) continue studies of individual genes to determine how genetic differences between Crohn's patients and healthy individuals contribute to the disease; 2) evaluate promising small molecules in disease - relevant studies and prioritize insights from genetics to help develop novel therapeutics; and 3) begin basic experimentation in animal models with Crohn's disease to provide the data necessary to begin testing new therapies in humans.
Carlos is a neuroscientist whose academic work has primarily focused on developing novel human MRI methods to evaluate disease progression and incident risk in stroke and neurodegenerative disease patients.
His analysis of all publicly available cancer mutations and integration with all solved computational models of human proteins has created a powerful roadmap for evaluating new mutations observed in patient tumors.
To evaluate the role of miR - 142 in the growth of human breast cancers initiated by the human BCSCs, we infected human BCSCs isolated from a patient - derived human breast cancer xenograft (PDX) with the anti-miR-142-3p-expressing lentivirus or the control lentivirus.
A veterinary clinical trial is a study conducted on veterinary patients and focused on evaluating the effects of new therapies, medical devices and diagnostic tests for eventual use in veterinary or human medicine.
With its internationally renowned school of veterinary medicine and its NCI - designated human cancer center, UC Davis is uniquely positioned to evaluate novel treatments for companion dogs with spontaneous tumors that may ultimately be effective in human patients with cancer.
Entresto, a highly effective drug used in treating human heart patients, is being evaluated at Auburn University's College of Veterinary Medicine for use with dogs.
While NSAIDs have not yet been carefully evaluated in dogs as a cancer prevention treatment, studies in humans have shown a decrease incidence in certain cancers (colon, prostate) in patients treated chronically with NSAIDs.
Results driven health and human services expert with distinct analytical skills and a wholly professional approach to evaluating overall effectiveness and providing the crucial decisions that result in smooth, seamless operations; seeks position where working knowledge will be fully utilized and expanded, with particular emphasis on: Managed Care / Health Services Risk Management / Patient Safety Consulting / Advisory Serv...