Sentences with phrase «even at the doses»

And to Gould's surprise, the metabolite did not cause side effects in the mice even at doses nearly 40 times higher than the antidepressant dose of ketamine.

However, they point out that, even at the doses absorbed from cigarettes, nicotine causes little if any harm.

TIC10 seems to be nontoxic to normal cells or mice even at doses 10 times higher that an observed therapeutic dose, however more research needs to be completed to satisfy FDA requirements prior to initiation of clinical testing.

Repeated use of ibuprofen will increase the risk of toxicity even at doses that would not be toxic in single exposures.

Not exact matches

Even though fish does not feature on my list for the weekdays as I depend on the previous night's dinner for my dose of lunch the next day at office, my folks at home need a small piece of fried fish to go with their afternoon meals of rice and curry.

I am amazed at how similar it tastes to the traditional style with pasta noodles, although I haven't had this kind of dish in a REALLY long time b / c of being vegan and gluten free, so my memory could be a little foggy But from what I can remember, this recipe was even better, and I love that you sub the zucchini noodles for the pasta noodles to get an even bigger dose of veggies in this dish!

This is done in a hospital setting, at prescribed doses + at set intervals, to watch for even the slightest reaction.

While we're at it we gain the benefits of a big dose of vitamin C, lots of fibre, B1, B2, Protein, Calcium, even Iron, to mention just a few.

I am not talking about the Arsenal fans that have been fighting among themselves or the Arsenal fans demanding that the club sack Arsene Wenger or even wanting the team to lose so the Frenchman is forced to quit, although I do think a heavy dose of chill pills is in order for a few of us at the moment.

the over-the-counter antihistamines diphenhydramine and doxylamine are safe at recommended doses during pregnancy, even for extended periods.

Even if conditions in the children's homes are chaotic and stressful, Educare's directors believe, the large dose of responsive care they experience each day at the center will allow them to transcend the potential ill effects of that instability.

Adults with coronary heart disease should make sure they get at least 1000 mg each day and even higher doses if they have high triglyceride levels.

If the first medicine doesn't seem to work, even at the highest dose, then a doctor may try a different medicine.

The University of California at San Francisco recently conducted a study where they discovered that early formula use can help women breastfeed for a greater length of time, even if doses are only in small amounts.

even when our girl has teeth cutting through, she's easily consoled with teething tablets or one dose of baby Tylenol, whereas before, we'd have to use several doses over the recommended period of time before they would calm down and finally fall asleep, since they seem to be at their worst in the evenings.

Even a high dose of synthetic oxytocin (Pitocin) is unlikely to trigger labor until a woman is at term.6

What's more, because these drugs may contain overlapping ingredients (combos of decongestants, antihistamines, cough suppressants and expectorants) your child can accidentally overdose from taking more than one medication at a time — like a cough syrup and cough and cold drops, say — even if you follow the correct dosing instructions for each one.

My son is potty trained at 26 months one day i said do you want to try underware and he was all for it he had wall e the robot and i said do nt peepee on walle or we have to take them off so he would go oh peepee and run to the potty chair i tryed before then but i just had to wate tell he was ready and watch all the signs he dose both on the potty we can even go on car rides he takes naps and he dosent wet he has had an accedent a few times and he would cry so i would tell him it was ok and let him pic out new underware nothing crazy he was just ready oh yeah we got him a book that had a poster in the back that every time he went potty he could pic out a sticker and put ut on the posster to note his progress and i gess that made him want to use the potty more to get more stickers he loved it i do nt k ow if that helps anyone but it did us good luck every one

«So it's important for us at birth to give a dose of Hepatitis B vaccine to every baby even before they get their regular vaccinations which start at 6 weeks.

He will receive another dose of adulation from Tory supporters tomorrow evening at a rally in Birmingham called «Boris Johnson's 2012: re-elected and Olympotastic».

It's even more repulsive in light of a recent study by Dr. Andrew Chang of Albany Medical Center, published in the Journal of the American Medical Association, showing opioids were no more effective at reducing pain for patients with broken limbs than a high - dose combination of the over-the-counter, non-addictive painkillers ibuprofen and acetaminophen.

«Although there was an overall dampening effect of alcohol on the prefrontal cortex, even at a low dose of alcohol we observed a significant positive relationship between dorsomedial and dorsolateral prefrontal cortex activity and alcohol - related aggression,» explains Denson.

«We'll certainly be looking at whether patients who manage their pain with cannabis can reduce their opioid doses over time or even wean themselves off opioids entirely,» he says.

Even more troubling, her study found a link between high blood levels of lycopene's chemical cousin, beta - carotene, and an increased risk of aggressive prostate cancer — not enough to justify avoiding carrots and other food sources of beta - carotene but an ominous sign that not all food - derived compounds are necessarily benign when taken at higher doses.

Even at the time of the sampling, the agency reported, residents could be exposed to large doses of contaminants for brief «peak» periods.

Last month, Mebias Discovery in Philadelphia, Pennsylvania, presented data on two new biased opioids that protected breathing in rats even at four times the effective painkilling dose.

Fruin's team at the Keck School of Medicine and the University of Southern California suspected that residents near LAX, the sixth busiest airport in the world, were getting exposed to excessive doses of pollution from airplanes even farther from the runways than previous research had considered.

The drug, daratumumab, proved generally safe in patients, even at the highest doses tested in the study.

However, when participants exercised at an intensity that was greater than 92 % of their HRmax during the high - intensity periods, the effect was even greater than at the lower intensity levels, indicating that there is a dose - response relationship even in the 85 - 95 % high - intensity zone.

* The ACC / AHA cholesterol treatment guideline recommends prescribing the strongest statins at high doses to most men older than 65, even those with no history of heart disease, or any major risk factor for heart attacks, and with normal cholesterol levels.

Citalopram, the most commonly prescribed drug among patients in the study, was not associated with an increased risk of arrhythmia, even at higher doses.

In some cases, patients» tumors develop resistance to Gleevec — either the Abl protein mutates so that the drug can no longer bind to it, or the protein accumulates in such quantities that the drug can't keep up, even at the highest dose.

All six of them quickly fell seriously ill with multiple organ trauma, even though the stuff had worked well on rabbits and monkeys at doses up to 500 times as large.

There isn't any other toxicant that we know of that even comes close to arsenic in terms of the number of health effects at the doses we're seeing and the numbers of people worldwide who are potentially exposed.»

At low doses, arsenic doesn't overwhelm body systems immediately or even cause death over the course of months.

Giving this once - monthly version of even the maximum recommended daily dose was equivalent to spending an afternoon at the beach in a bathing suit, Dong said.

Finally, these benefits emerged without any adverse side effects, even at SW033291 doses much higher than would be required for 15 - PGDH inhibition.

Sucralose has shown no carcinogenic effects in animals, even at high doses.

The findings confirm that lead exposure, even at low doses, is associated with poor school performance.

Biophysical studies have shown that the damage arising to cells from an exposure to ionizing radiation declines in a linearly manner with decreasing dose, with some damage still occurring even at the lowest doses.

At the end of the trial period, the researchers found that 41 of the 49 therapy recipients could tolerate the 800 mg dose safely — and 24 of them could even handle 1400 mg.

Studies of the Aum Shinrikyo survivors link exposure «even at really low doses» to symptoms such as nightmares, headaches, drowsiness, confusion, memory deficits, irritability, and depression — a syndrome called organophosphorus - ester - induced chronic neurotoxicity (OPICN).

The researchers also showed that the nitroxide BASP nanoparticles are not harmful to mice even at very high doses.

But even more damning from a pharmacological perspective, the team found the same effect at all doses of either herbicide or GM maize.

For these reasons, under dosing is common, leaving children at increased risk for bleeding episodes and even death.

«This really does demonstrate that when someone is exposed concurrently to a whole host of nasty chemicals even at low doses, there are consequences that are not going away,» Shetty said.

All of these foods contain the inositol phosphate IP5 — a compound that even at low dose limits the supply of blood to tumor cells and inhibits tumor growth in mice, according to new findings.

Even in nanomedicine, which is one of the best new methods for delivering drugs to a tumor, only about one percent of a dose of nanoparticles will successfully arrive at the intended tumor site, while the rest are filtered out by the immune cells of the liver and spleen.

Increased Smad1 / 5 phosphorylation was observed even at a low dose (6 pg) of mutant ACVR1.

The situation is even clearer for children, who are at greater risk than adults from a given dose of radiation (Figure 4), both because they are inherently more radiosensitive and because they have more remaining years of life during which a radiation - induced cancer could develop.