To model the neurons, we'd have to measure from them, but this turns out to be more difficult for C. elegans than for mouse or
even human neurons.
Not exact matches
If the
human quest is reduced to electrons dancing along wires and computational patterns crossing a population of
neurons, does such a «story» justify
even caring whether our society attains the success of a complex adaptive system?
In another example, he uses the example of
human vision: the cortex predicts what should be seen and the mind fills in the gaps; in other words interpretation takes place according to expectation, so context
even changes the way that
neurons function.
As a result, the cerebellum in apes and
humans contains far more
neurons than that of a monkey,
even when the brain is scaled up to the size it would be in an ape.
There are between 100 billion and 200 billion
neurons in a
human brain, so
even at only a second per
neuron, this will require tens of thousands of years.
Since olfactory sensory
neurons regenerate throughout life,
even in
humans, the investigators were able to measure
neuron regeneration in specific animal models.
«Worms, mice,
humans, and
even fruit flies show similar effects of intoxication at similar alcohol concentrations,» he says, and
human neurons contain a switch similar to that in C. elegans.
Their end goal is to identify specific populations of
neurons in the fruit fly brain that are necessary for emotion primitives — and whether these functions are conserved in higher organisms, such as mice or
even humans.
The method could also help biologists understand how tissues change subtly during embryonic development — and
even help map the maze of
neurons that wire the
human brain.
Researchers at the Salk Institute for Biological Studies recently found that the DNA sequence in
human neurons can vary not only from that of the rest of the body but
even from one brain cell to the next.
A region of the gene that produces the PACAP38 protein has held nearly constant,
even in
humans, presumably because the protein plays diverse roles in
neuron communication and is essential for normal development of the cerebellum, affecting brain cell migration, for example.
These so - called bioreactors, and the mini-brains they foster, should open other new and valuable windows into
human brain development, brain disorders and drug testing — and perhaps
even produce
neurons for treatment of Parkinson's disease and other disorders, the investigators say.
«On the basis of individual
neurons of the brain,
humans may indeed have a far more active, or
even more complex, transcription profile than chimpanzee,» the authors note.
«
Even though they're mice, we see these
human cells that appear to be connecting to other
neurons.»
Illogical as it is, the idea that
neurons could be wirelessly and remotely activated by someone other the owner of those
neurons disturbs me
even though I know drugs are commonly used to do much the same thing in
humans.
In terms of brain simulation, the challenges are
even bigger: The world's fourth most powerful supercomputer took 40 minutes to model one second of brain activity in a simulated network containing 1.73 billion
neurons and over a trillion synapses, yet this represents just one per cent of neuronal networks in the
human brain.