Sentences with phrase «even rare alleles»

The large sample size combined with sensitive sequencing techniques that detected even rare alleles and infections by multiple parasites enabled researchers to find an allele - specific response that smaller studies had missed.

Not exact matches

Some of the associated variants were super rare (MAF < 1 %), suggesting that genotyping studies like this are well - powered to detect associations even at allele frequencies below one percent.

At low - density lipoprotein receptor (LDLR), carriers of rare non-synonymous mutations were at 4.2-fold increased risk for MI; carriers of null alleles at LDLR were at even higher risk (13-fold difference).