Telomeres gradually break down and shrink as cells age,
eventually leading to cell death which is a normal part of human growth and aging.
In the long term, this damages the neurons,
eventually leading to cell death.
Oxygen free radicals are toxic for cells, since they cause damage to cell membranes surrounding living cells as well as their nucleus and other inner organelles,
eventually leading to cell death.
Not exact matches
The disease is caused by a genetic mutation that
leads to abnormal clumps of protein in the brain,
eventually resulting in the atrophy and
death of nerve
cells.
«After circulatory arrest, spreading depolarization marks the loss of stored electrochemical energy in brain
cells and the onset of toxic processes that
eventually lead to death.
Telomeres shorten every time a
cell divides, and ultimately the loss of telomeres
leads to cellular senescence, where
cells cease
to divide, and
eventually,
cell death.
Plaque hinders neuronal activity by gumming up synapses (spaces between
cells through which chemical or electrical information is transmitted),
eventually damaging nerve
cell branches and
leading to neuronal
death.
«Our studies show that broken - down components of the nuclear transport machinery
lead to traffic jams within brain neurons of essential information and
eventually brain
cell death,» says Grima.
CAMBRIDGE, Mass. — Scientists know that in patients with Parkinson's disease, certain proteins in the brain form clusters that somehow contribute
to cell death and,
eventually,
lead to the onset of the disease's debilitating symptoms.
The mutant mice had fewer myocardial
cells and disruptions of the muscle integrity that
eventually led to prenatal
death.
These retinal
cells are the type that are killed off in macular degeneration,
eventually leading to the
death of photoreceptors, and the gradual loss of central vision.
Deletion of an essential gene from a
cell eventually leads to the
death of this
cell or a severe proliferation defect.
Once the T
cell count is less than 200
cells per ml of blood, symptoms of AIDS begin
to manifest and the patient is at high risk of recurrent infections that will
eventually lead to death.
This «bioartifical liver support», where a patient's blood passes through a small reactor seeded with pig liver
cells, removes waste chemicals from the blood that would otherwise build up inside the patient and
eventually lead to coma and
death.
This is especially dangerous because red blood
cells can uptake carbon monoxide faster than oxygen so if there is a lot of carbon monoxide in the air, it can replace oxygen in
cells,
leading to injury, tissue damage and
eventually death.
Also, a 2012 study published on the Medical Journal 3 Biotech shows that the anti-cancer compounds in mushrooms play a crucial role as a reactive oxygen species inducer, mitotic kinase inhibitor, antimitotic, angiogenesis inhibitor, topoisomerase inhibitor all
leading to apoptosis (
cell death) and
eventually checking cancer
cell proliferation (4).
These damaged
cells eventually crowd out the good and may
lead to death if the condition can't be treated.
In CAH, continuous liver inflammation and
cell death eventually lead to the replacement of the normal liver tissue with scar tissue.
Any time the seizures are too frequent they can cause a process call «kindling» in which further (non-epileptic) brain
cells are affected adversely
leading to the next set of seizures occurring even sooner or lasting longer.8
Eventually some dogs have very frequent clusters of seizures happening multiple time in one day, or go into a continuous seizure (status epilepticus) which is life threatening and can
lead to permanent brain damage or
death.