Sentences with phrase «eventually leads the cells»

The blood sugar roller coaster caused by regular consumption of too many carbohydrates or the wrong kind of carbohydrates (refined and processed) and / or stress, produces chronically - elevated levels of insulin, which eventually leads the cells to lose their sensitivity to insulin and no longer respond normally.

Not exact matches

Gradually organic chemicals were synthesized and eventually self - replicating complex molecules evolved, enabling the evolution of living cells, leading to multi - cellular organisms, plants and animals.

Spontaneous self - organization is invoked by biochemists in the evolution of the prebiotic world in which a variety of atoms assembled into organic molecules eventually giving rise to molecules of RNA, DNA and proteins which led to further complex assemblies and eventually to cells.

Knowing how these cells mature during development might lead to a better grasp of just how to replicate that process in the adult brain, which could eventually pave the way to strategies that rejuvenate aging circuits, Donato said.

The disease is caused by a genetic mutation that leads to abnormal clumps of protein in the brain, eventually resulting in the atrophy and death of nerve cells.

Her new projects could eventually lead to light - based technologies used to improve drugs or to create new tests to find cancerous cells.

One finding was that strep eventually led to massive production of a certain kind of immune cell, Th17, along with inflammation of the brain.

Boscia, whose cell phone shows an olive tree from his father - in - law's grove as its screen saver, is leading an epic battle against a mountain of bureaucracy and funding cuts to institute an open - air research center to study the disease and eventually find a way to stop it.

«After circulatory arrest, spreading depolarization marks the loss of stored electrochemical energy in brain cells and the onset of toxic processes that eventually lead to death.

Telomeres shorten every time a cell divides, and ultimately the loss of telomeres leads to cellular senescence, where cells cease to divide, and eventually, cell death.

«Retinal nerve cells grown in the lab: Work could eventually lead to cell transplants for people blinded by glaucoma, MS.» ScienceDaily.

If it weren't for telomerase, this gradual shortening would eventually lead to the complete loss of the telomeres in cells that replicate frequently during a life span, and thus the gradual erosion of the genes themselves.

«And, eventually it could lead to the development of cell transplant therapies that restore vision in patients with glaucoma and MS.»

«We hope that these cells can eventually lead to new treatments for glaucoma and other forms of optic nerve disease.»

This led me to enter the field of developmental and cell biology, and to eventually discover cyclin as a key regulator of the cell cycle.

In summary, less Cdh1 prevents the normal function of APC / C, which eventually inhibits the degradation of PAX3, potentially leading to unregulated cell proliferation and cancer (melanoma in skin cell models).

Plaque hinders neuronal activity by gumming up synapses (spaces between cells through which chemical or electrical information is transmitted), eventually damaging nerve cell branches and leading to neuronal death.

The researchers conclude this technique could eventually lead to new ways to prepare vast numbers of cells for the coordinated manufacture of gene therapies.

For example, smoking changes the epigenetic makeup of lung cells, eventually leading to cancer.

Donn says: «When the enzyme is blocked, ammonia accumulates in the chloroplasts, eventually leading to the destruction of the chloroplasts and plant cells, so that the plants die.»

For example, the protein can became permanently active, and such activity would lead to overgrowth of cells and eventually to cancer.»

The results challenge accepted ideas about how stem cells age and may eventually lead to new ways to prevent graying and treat the more serious conditions caused by genotoxic stress, such as cancer.

Even a Harvard stem cell scientist who reviewed a meeting abstract Moriguchi provided — the abstract that eventually led to the crumbling of his claims — did not pick up on the deception.

Telomeres gradually break down and shrink as cells age, eventually leading to cell death which is a normal part of human growth and aging.

Published May 4, 2015, in Nature Neuroscience, the new findings may eventually lead to treatment strategies targeted for the underlying causes of schizophrenia and related disorders, said the study's corresponding author Scott Soderling, an associate professor of cell biology and neurobiology in the Duke School of Medicine.

«Our studies show that broken - down components of the nuclear transport machinery lead to traffic jams within brain neurons of essential information and eventually brain cell death,» says Grima.

With the honeycomb shape, this eventually led to an oval ring of cells within the pore — with the majority aligned along the long axis.

It described the growth in cell cultures of the virus that causes AIDS, a breakthrough which led eventually to a blood test for HIV infection.

«Through examination of Arabidopsis ovules by highly sensitive live - imaging, we were able to see that successful fertilization of the two female gametes triggers an unprecedented cell fusion between the persistent synergid cell and the endosperm (SE fusion), which eventually leads to inactivation of the persistent synergid cell.»

Without these cells, the immune system recognizes a newly transplanted lung as harmful and mounts an attack that eventually can lead to rejection of the organ.

The destruction of cells lining the gut leads to abdominal cramping, watery diarrhea, and eventually bloody diarrhea.

This result, effectively a method for blocking the spread of alphaviruses between cells, is one that could eventually lead to a single vaccine that protects against multiple viruses.

If the approach also works with human cells, it could eventually lead to cell therapies for diseases like inherited leukodystrophies — disorders of the brain's white matter — and multiple sclerosis, as well as spinal cord injuries.

The 28 groups that will eventually make up the CRG will be organised around five main programmes — Gene Regulation, Development and Cell Biology, Cell Differentiation and Cancer, Genes and Diseases, and Bioinformatics and Genomics — each of which will be headed by a senior scientist leading his or her own group.

The other end of the receptor sets off a chain reaction when such a B cell is bound, eventually leading the T cell to destroy the cancerous cell.

The test tube finding, reported in the current Cell, could help explain the formation of prions — the tangled proteins that are implicated in mad cow disease and several human brain disorders — and eventually may lead to a way to smooth out these rogue proteins.

Now, a study led by Washington University School of Medicine in St. Louis describes a newborn screening test that identifies infants with NPC, an often fatal condition in which cholesterol builds up and eventually destroys brain cells.

When these cells are illuminated by a strong light, a change in the structure of melanopsin triggers a molecular cascade that eventually leads to an influx of calcium ions into those neurons and an electrical pulse.

The group succeeded in visualizing for the first time, how the cytoskeleton of plant egg cells is disassembled after fertilization and then reorganized to create a polarity in the cell that eventually leads to asymmetric cell division.

Finally, the MTs gathered around the nucleus after about 18 hours and distributed the chromosomes, eventually leading to cell division after about 22 hours,» she continues.

The donation will support an innovative program with three leading medical research groups and, for the first time, will introduce gene editing and stem cell therapies to effect treatments and, eventually, a potential cure for Huntington's disease.

Better understanding of the beta - cell proliferation process eventually may lead toward therapies for diabetes patients, whose supplies of these cells often shrink over time, says Rohit Kulkarni, M.D., Ph.D., a Joslin Senior Investigator and senior author on a paper about the work published in the journal Cell Metabolcell proliferation process eventually may lead toward therapies for diabetes patients, whose supplies of these cells often shrink over time, says Rohit Kulkarni, M.D., Ph.D., a Joslin Senior Investigator and senior author on a paper about the work published in the journal Cell MetabolCell Metabolism.

CAMBRIDGE, Mass. — Scientists know that in patients with Parkinson's disease, certain proteins in the brain form clusters that somehow contribute to cell death and, eventually, lead to the onset of the disease's debilitating symptoms.

Their research found that a variety of naturally - occurring mutations in the DNA cells can initiate different sequences of mutations that eventually lead to breast cancer.

The discovery eventually led to the uncovering by others of two additional signaling pathways in mammalian cells that, together with Ire1, help maintain equilibrium in the face of stress, averting a host of diseases.

The mutant mice had fewer myocardial cells and disruptions of the muscle integrity that eventually led to prenatal death.

This creates a toxic environment within the brain that damages nerve cells and eventually leads to the debilitating symptoms of MS.

These retinal cells are the type that are killed off in macular degeneration, eventually leading to the death of photoreceptors, and the gradual loss of central vision.

Deletion of an essential gene from a cell eventually leads to the death of this cell or a severe proliferation defect.

Once the T cell count is less than 200 cells per ml of blood, symptoms of AIDS begin to manifest and the patient is at high risk of recurrent infections that will eventually lead to death.