Sentences with phrase «evidence of apoptosis»
Morphologic examination of the Hoechst - stained cell preparations at 16 hours after treatment with 20 nmol / L rapamycin showed morphologic evidence of apoptosis, such as nuclear condensation and fragmentation in ALCL cells (A, bottom right).
http://cancerres.aacrjournals.org/ Not exact matches
The protein encoded by the PIK3C2G gene belongs to the phosphatidylinositol -4,5-bisphosphonate 3 - kinase (PI3K) family, which plays a critical role in cancer.28 Experimental evidence suggests that activation of PI3K signaling enhances production of COX - 2 and PGE2, which results in inhibition of apoptosis in colon cancer cell lines that can be restored with NSAID - mediated blockade of PI3K.29
To search for more evidence of tumor cell apoptosis, a TUNEL assay was performed on mice tumor sections.
A number of lines of evidence indicate that in a cancer context, like in development (Daxx - null genotype is an embryonic lethal condition in which the embryos die by age E9.5 [15], due to global apoptosis), DAXX may have a pro-survival role.