A review of
the evidence on antidepressants has been hailed as the final word on these drugs, but questions remain for people with less severe depression
Not exact matches
There is enough
evidence that
antidepressants cause increased risk of suicide and violence for the U.S. Food and Drug Administration and its Canadian counterpart to require that drug companies include a «black box» warning to that effect
on their packages.
An expert
on the placebo effect, Kirsch has unearthed
evidence that
antidepressants do not correct brain chemistry gone awry.
Indeed, given the lack of
evidence as to whether SSRIs and other
antidepressants have any causal effect
on fetal neurodevelopment, it's possible that SSRIs could actually help a developing fetus whose mother is depressed, says Jay Gingrich, a psychiatrist at Columbia University who has no affiliations with any pharmaceutical companies.
Antidepressants, such as venlafaxine (VFX), which are considered emerging environmental pollutants, are increasingly more present in the marine environment, and recent
evidence suggest that they might have adverse effects
on fish behaviour.
A review of published
evidence on the effect of
antidepressants on suicidal behaviour and violence in healthy people is published in Journal of the Royal Society of Medicine with the authors reporting «
antidepressants double the occurrence of events in adult healthy volunteers that can lead to suicide and violence.»
Research has indicated that
antidepressants are currently prescribed primarily
on the basis of anecdotal
evidence shared between patient and doctor.
These advances have had limited impact
on community care, with current data indicating high unmet need28 - 30 and poorer quality and outcomes for community treatment compared with efficacy studies.31, 32 We address these gaps by evaluating a quality improvement intervention aimed at improving access to
evidence - based treatments for depression (particularly CBT and
antidepressant medication) in primary care settings.
There is a growing
evidence base in support of the effectiveness of acupuncture for a range of musculoskeletal conditions11, 12; however, despite its widespread use by participants13 there has been limited
evidence for acupuncture as an effective treatment option for depression.14 Patients with strong preferences for psychotherapy or counselling for depression are not likely to engage in
antidepressant treatment, 15 yet the
evidence for counselling as a treatment for depression is limited16 despite widespread utilisation in primary care in the UK, with around 90 % of general practices providing
on - site counselling services.17 To address this
evidence gap, a randomised controlled trial Acupuncture, Counselling or Usual Care for Depression (ACUDep) compared acupuncture or counselling to usual care as treatments for primary care patients with ongoing depression.18 The results showed that acupuncture and counselling were clinically effective in reducing depression in the short to medium term.