Sentences with phrase «evolved drug resistance»

If these peptides are developed for therapeutic use, the researchers anticipate that they could be used either in stand - alone therapy or together with traditional antibiotics, which would make it more difficult for bacteria to evolve drug resistance.

«Hsp90 inhibitors might actually help cancer cells evolve drug resistance.»

«Strains with high levels of Hsp90 could rapidly evolve drug resistance, while the ability of strains with low levels of Hsp90 to evolve resistance was impaired,» says Cowen.

Not exact matches

The drugs we used to treat the infections were not widely present before humans started using them, now there is a resistance to them programed into the microorganism's DNA... they EVOLVED to be resistant.

For example, bacteria would typically develop drug resistance by evolving a mutation that breaks down the drug.

Newly discovered mutations are helping tuberculosis to stay infectious while evolving resistance to multiple drugs

Combining drugs from multiple classes into so - called cocktails makes it harder for the rapidly mutating virus to evolve resistance, but adding a single drug to a failing cocktail quickly breeds resistance to it, too.

The research explains how tumors evolve and cause cancer resistance to drugs designed to match the patient's unique genomic makeup.

At the same time, bacteria have continued to evolve resistance to all of the currently available drugs, creating the current critical situation.

A comparison of the dopamine receptors in the coke caterpillar with those of the silkworm, which doesn't feed on cocaine plants, revealed that E. noyesi has evolved resistance to the effects of the drug.

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve.

Some patients respond to the drug for years, but in other patients, the treatment either fails early, or the cancer evolves resistance.

Greenbaum believes it might be more difficult for malaria to evolve resistance to a drug aimed at a protein in its host rather than at one of its own.

By now, some parasites have evolved resistance to the drug: genetic adaptations that allow them to expel chloroquine from their food vacuoles 40 to 50 times faster than their drug - sensitive kin.

This «panic» response enables them to rapidly evolve resistance to drugs.

But this variant of the bacterium has evolved so much resistance to antibiotics that to combat it doctors must rely on drugs that haven't been widely used in decades.

You know, they are trying to find these drugs that maybe bacteria have not evolved resistance to, and they found some really promising ones.

But some studies have linked it with a risk of mastitis (udder infection) in cows, requiring the use of antibiotics that may in turn be contributing to the evolving resistance of bacteria to the drugs.

It might also evolve resistance by exposure to the drug.

At the beginning of the HIV epidemic, drug resistance to treatment evolved quickly and predictably across all patients.

Most recently, postdoctoral researcher Leah Cowen has shown that Hsp90 allows yeast to rapidly evolve resistance to antifungal drugs.

Plasmodium will evolve resistance to the partner more quickly, driving both drugs towards uselessness.

Howard Hughes Medical Institute researchers chiseling away at the problem of antibiotic resistance now have a detailed explanation of how the drugs» main cellular target in bacteria evolves to become...

Each time a new antimalarial drug has been introduced, the parasites have evolved resistance to it.

Assist disease control by providing up - to - date geographical information about known and newly - emerging forms of drug resistance, by examining genetic variation in the context of how whole pathogen genomes are evolving rather than as fragmentary information about individual genetic changes or polymorphisms.

Cowen also found that once fungal strains became drug resistant, they could eventually evolve the ability to retain this resistance independent of Hsp90.

As we improve the resolution and accuracy of our analyses of genetic variation, we'll be able to delve deeper into key scientific questions like how populations of Plasmodium parasites are evolving, migrating to different locations and developing drug resistance.

Recent studies looking at the genome of the malaria parasite could help scientists understand how drug resistance has evolved — and develop the tools needed to keep it in check.

There are hundreds of variants that evolve and gain resistance to drugs very quickly, making it nearly impossible to become fully immune or to vaccinate against all of them.

The emergence of antibiotic - resistant gonorrhea is considered one of the most pressing problems in infectious disease — just two years ago, the Centers for Disease Control and Prevention named it an «urgent threat,» and indeed, gonorrhea seems to be evolving resistance to drugs at quite a rapid clip.