Sentences with phrase «excessive oxidative»

It is a therapeutic support nutrient for conditions marked by excessive oxidative stress.

Cardiomegaly is due to excessive oxidative stress (from either intense exercise or excess calorie intake, especially excess saturated fats and polyunsaturated fats) combined with antioxidant deficiencies (e.g. vitamin E, selenium, glutathione, C, zinc, copper).

As a result, intake of pears has now been associated with decreased risk of several common chronic diseases that begin with chronic inflammation and excessive oxidative stress.

Since, as suggested above, this «collateral damage» involves mitochondrial function and oxidative processes, these other complementary interventions could take the form of other modalities we have successfully used for years to both enhance mitochondrial function and reduce excessive oxidative activity.

The formation of plaque along our blood vessel walls starts with chronic, excessive oxidative stress and inflammation.

Not exact matches

Excessive inflammation and oxidative stress are risk factors not only for the development of chronic diseases like type 2 diabetes, but also for the development of cancers.

Fat cells produce excessive reactive oxygen species, which can damage cells in a process called oxidative stress.

«Oxidative stress can cause damage to the building blocks of a cell, resulting in excessive cell proliferation, in the case of cancer or cell death, in the case of neurodegenerative diseases like Parkinson's,» said Mark Hannink, a professor in the Department of Biochemistry and an investigator at the Bond Life Sciences Center at MU.

However, excessive generation of ROS and / or a fall in antioxidant defences can lead to indiscriminate damage, resulting in cellular oxidative stress [27].

Accelerated production of GH is bad, it activates excessive insulin IGF - 1 axis which increases T2D, reduces SIRT / DAF / FOXO genes who activate important oxidative stress genes (SOD, NRF2...)- But LOSS of GH is just as bad Hutchison - Guilford»S progeria children who die at 11 to 15 years old have an extreme accelerated aging (they look like children with ghastly «dying look» of very old people phenotype).

In Ames dwarrf, Snell Dwarf mice, Klotho mice, GHKO mice who have little IGF and GH; and live longer than wild - type; we see that indeed insulin and glucose / nutrient / energy pathways (which create oxidative stress through excessive nutrient via elevated glycation blood glucose creating high glycated albumin and hemoglobin), that aging is acted on by IGF through hormones, GFs, GHs, acting on insulin signals, which act on survival genes (DAF / SIRT / FOXO).

Although many years ago we found that reactive oxygen species (ROS) are required for full expression of hippocampal LTP and memory, it is clear that the aged and diseased brain handle ROS much differently as many studies have pointed to a role for excessive ROS and oxidative stress in age - related cognitive decline and impaired memory associated with Alzheimer's disease (AD).

So, the tissues of the body are now at risk of receiving both excessive glucose and fat, which is now causes the oxidative stress and the inflammatory response.

Even the healthiest among us have some free radicals in our systems, but when free excessive radicals are formed in the body, the harmful condition known as oxidative stress occurs, possibly leading to disease.

These antioxidants are powerful and aid in the reduction of excessive ROS and oxidative - stress within the body, which have been linked to nearly all human diseases.11.5

Not only is excessive inflammation and oxidative stress linked to nearly all known physical maladies but it also contributes to decreased insulin sensitivity ultimately wreaking havoc on health, physique, and performance attributes.

When the cells are unable to detoxify, they end up accumulating excessive toxins and oxidative stress that damages the mitochondria and DNA.

Diseases of old age: Alzheimer's, heart disease, diabetes, dementia and cancer are the result of oxidative stress coming from poor lifestyle, poor diets and mental - emotional stress.Cigarette smoking, excessive alcohol consumption, excess sugar and salt, processed foods containing chemicals create a chemical and heavy metal burden on the body responsible for diseases of old age.It is possible to avoid all the illnesses.

Recurring, excessive postprandial glycemia could decrease blood HDL - cholesterol concentrations, increase triglyceridemia, and also be directly toxic by increasing protein glycation, generating oxidative stress, and causing transient hypercoagulation and impaired endothelial function (21, 22).

Training and dieting to achieve extremely low levels of body fat is demanding on the human physiology, thus, supplying the body with the precise nutrients found in Palm Fruit to stave off oxidative stress, elevated cortisol, and excessive inflammation is a priority.

Excessive alcohol consumption can cause oxidative damage to the Leydig cells in the testes.

Similarly, unsupported oxygen metabolism due to lack of antioxidant nutrients has been shown to result in oxidative stress, excessive formation of free radicals, and a metabolic environment that increases risk of cancer development.

Of course, as with inflammation, oxidative phenomena play a valuable role in the brain, with only prolonged or excessive production being a problem:

Oxidative stress (which is often related to deficient intake of antioxidant nutrients) and excessive inflammation (which can also be related to deficient intake of anti-inflammatory nutrients) are common risk factors for a wide variety of health problems.

When fed in excessive amounts (5g of garlic per kg of the dog's body weight), garlic can cause oxidative damage to Fido's red blood cells, leading to a condition called Heinz body anaemia, a complex disease that requires professional diagnosis and treatment.

After the rods die, the excessive «left - over» oxygen is toxic, causing oxidative damage and ultimate death of cones.