Sentences with phrase «excitatory synapse»

Administration of a positive allosteric modulator of the type 1 metabotropic glutamate receptors mGluR1 during the first postnatal week restored DA neuron excitatory synapse transmission and partially rescued the social preference defects, while optogenetic DA neuron stimulation was sufficient to enhance social preference.

Afadin, a ras / rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampus.

Afadin, A Ras / Rap Effector That Controls Cadherin Function, Promotes Spine and Excitatory Synapse Density in the Hippocampus.

Interestingly, Sharma says, the team found that LRP6 was only found on a specific kind of synapse known as an excitatory synapse, suggesting that it enables the Wnt pathway to tailor its effects to just one synapse type.

Astrocytes, named for their star - like shape, are ubiquitous brain cells known for regulating excitatory synapse formation through cells.

Not exact matches

Chemical synapses, which are the most abundant type of synapse, can be either excitatory or inhibitory.

The idea that the balance between excitatory and inhibitory inputs depends on astrocyte signals gains strong support with this new study and suggests a pivotal role for astrocytes in the development of neurological disorders involving impaired inhibitory synapse transmission.

Isolated excitatory spines annotated from a single cortical pyramidal neuron with Vaa3D Synapse Detector program developed in collaboration with the Allen Institute for Brain Science (Unpublished, Dan Iascone)

In a series of electrophysiological studies, Zoghbi's team further found that neurons from animals with depleted MECP2 levels have reduced electrical activity due to a smaller number of excitatory synapses, whereas cells from animals carrying an extra copy of the gene have increased electrical activity because of an increase in synapse number.

Neurotransmitters are endogenous (internal) chemicals that transmit signals from a neuron to a target cell across a synapse, potentiating some kind of action, whether it be inhibitory or excitatory.