The researchers monitored their rate of
exhaled nitric oxide, a marker of airway inflammation.
Nitric oxide levels did not change at all among the group who thought the smell was therapeutic, but those who believed it to be asthmogenic had an immediate rise in
exhaled nitric oxide that continued to climb.
In an asthma patient, the amount of
exhaled nitric oxide in a breath test provides a good indication of how well the patient's medication is working.
After controlling for asthma, smoking, diet, demographics and other factors, researchers found that
exhaled nitric oxide levels were lower in excessive drinkers than in adults who never drink, and the more alcohol an excessive drinker consumed, the lower the level of nitric oxide.
The study found no clear change in blood eosinophils with dupilumab therapy; however, other biomarkers decreased, including fractional
exhaled nitric oxide, thymus and activation regulated chemokine, immunoglobulin E and eotaxin - 3, confirming the biologic activity of dupilumab.
Not exact matches
The goal of our current studies is to understand the role of
nitric oxide (and other markers in
exhaled breath) in lung physiology and in the pathophysiology of lung diseases like pulmonary hypertension and asthma.