Two studies have identified groups of girls
exhibiting chronically high levels of antisocial
behavior across childhood and early adolescence and having an increased risk for continued antisocial
behavior.60 In addition, Odgers and several colleagues found that 7.5 percent of all girls between the ages of seven and fifteen displayed an early - onset of offending that persisted into adolescence and that this pattern was similar to boys of the same age.61 Other studies suggest that although strongly
aggressive behavior in girls
before the age of seven is rare, continuity of offending for such girls may be stronger than that among comparable boys and that such early problem
behavior in girls should be considered a significant warning sign of potential future problems.62
A fourth drug, guanfacine, which recently was approved by the FDA in a 24 hours form (Intuniv) for ADHD has been explored in an open trial with 15 of 17 patients
exhibiting significantly decreased
aggressive behavior; however, this medication requires monitoring of blood pressure and cardiovascular parameters - electrocardiogram is required
before starting due to potential risk of heart block.