Participants classified as having dementia satisfied DSM - IV (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) criteria, had dementia severity ≥ 1.0 on the Clinical Dementia Rating Scale and
exhibited symptoms of dementia for at least 6 months.
It is known that plaque exists as a normal byproduct of metabolic activity in the brain and is not properly cleared in
those exhibiting symptoms of dementia.
Not exact matches
Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that
exhibits the
symptoms and neurodegeneration associated with the most common genetic forms
of frontotemporal
dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), both
of which are caused by a mutation in the a gene called C9ORF72.
«If scientists want to test drugs for
dementia, Alzheimer's or autism, ideal models would react similarly to humans in regards to the reduction
of symptoms, outbreak
of side effects, such as enduring the same lesions as humans do, or
exhibiting similar behavioral characteristics,» said Latham, who's with the College
of Agriculture and Natural Resources and an MSU AgBioResearch scientist.
Do these wild animals
exhibit the same
symptoms of memory loss that characterize
dementia in humans?