Additionally, with each passing year, veterinary science is improving
on existing vaccines as well as increasing the ability to prevent an even wider array of contagious diseases.
For some researchers the big goal is to bump up the effectiveness
of existing vaccines, most of them made from chemically - killed influenza particles or proteins extracted from such particles (see «Anatomy of a killer virus»).
Bäumler says that if his team's scenario is true, it suggests a new method for fighting S. enteritidis, which is difficult to detect: immunize chickens against one of the related strains
with existing vaccines, and the birds may also be able to ward off infections that endanger humans.
Understanding what combination of mutations could transform H5N1 into a human pandemic virus gives epidemiologists a leg up on preparing countermeasures; they can, for example, test
existing vaccines against the new strain.
My hope for the future is for major new reductions in childhood deaths — they could fall by half by 2025 if we could
deliver existing vaccines, malaria treatment, and today's other lifesaving tools with 90 percent penetration to those at risk.
Extreme shifts in surface proteins explain
why existing vaccines offer no protection against the new avian flu.
Other scientists add that it should force governments to
rethink existing vaccine technologies, which are only capable of supplying vaccine six months after a pandemic starts, and of producing enough vaccine for a small fraction of the world population.
1) Facilitate safe off - label use
of existing vaccines — Support collaboration between the zoological community and conservationists in the field to determine the safety as well as efficacy of existing distemper vaccines that could be, at a minimum, administered opportunistically to endangered wild carnivores whenever they are being handled (e.g. during radio - collaring exercises or when being translocated to mitigate human - wildlife conflict).
In a dissenting opinion, they accused the court of imposing «its own bare policy preferences» to protect vaccine manufacturers and said it was important for companies to be pushed, at times by litigation, to improve
on existing vaccines.
The existing vaccine will not protect at all against the new organism, therefore vaccination will be totally ineffective as a means of prevention.
Orme and his research team in Fort Collins investigated whether
the existing vaccine for TB, which goes by the acronym BCG (bacille Calmette - Guerin), worked equally well against different clinical strains of tuberculosis.
The committee also voted on whether to cut two
existing vaccine - research objectives from the plan.
Almost
all existing vaccines directly target a pathogen — whether it's a virus, a bacterium, or a parasite.
Gregory Poland, the head of the Mayo Clinic's Vaccine Research Group, has been working to unite the fields of genomics and vaccinology — what he calls «vaccinomics» — for 22 years, in part because he has never been fully pleased with
the existing vaccine paradigm.
The most dangerous experiments involve strains that are unfamiliar to our immune systems; neither our natural defenses nor
existing vaccines can protect us against them.
In 2002, when GAVI convinced suppliers to manufacture extra courses of
an existing vaccine against Haemophilus influenzae type b, poor countries were slow to buy it.
Rhesus macaques that received the inhibitor were protected against infection from the monkey equivalent of HIV and fought off viral doses higher than
any existing vaccine could touch, Farzan says.
The key ingredient in
the existing vaccine against whooping cough, or pertussis, is an inactive form of pertussis toxin.
Littler is hopeful that understanding the natural diversity of pertussis - like toxins could help improve
existing vaccines and create new ones.
«We don't think that any of
the existing vaccines are effective,» acting CDC Director Richard Besser said yesterday at a press conference.
«The really good point about this study is that it shows how genetics, informed by genome sequence analysis of large cohorts, can help us understand not only cancer and rare genetic diseases but also how to get the most out of
existing vaccines or develop new ones against recalcitrant foes such as HIV (and even against non-viral agents such as malaria).
Ultimately, the project aims to develop tests and approaches that will allow acceptance of the «consistency approach» for
existing vaccines by the regulatory agencies and thereby significantly reducing in the future the use of animals for batch testing in routine vaccine production.
This is the first indication that there may not be cross-protection with
the existing vaccine.
Racing greyhounds are routinely vaccinated for kennel cough, but mounting evidence suggests that
existing vaccines are marginally beneficial and do not provide lifetime protection.
The existing vaccine for H3N8 does not prevent the new H3N2.