By teasing apart the structure of an enzyme vital to the parasites that cause toxoplasmosis and malaria, Whitehead Institute scientists have identified a potentially «drugable» target that could prevent parasites from entering and
exiting host cells.
Not exact matches
In particular, they have examined the ways in which viruses hijack
cell proteins to help regulate their
exit and spread from the
host cell through the budding process.
«Bacterial and
host cell proteins interact to regulate Chlamydia's «
exit strategy»: New research suggests major role for calcium ion signaling in release of Chlamydia from infected
cells.»
«One of the important points to come out of this work is that it implies a complex of multiple chlamydial proteins that function together to regulate
exit mechanisms from
host cells,» the authors further explain.
Hemagglutinin (HA) and neuraminidase (NA) are the two predominant viral glycoproteins found in the viral envelope, and are the primary targets of the
host immune system and are key factors in the entry and
exit of influenza particles from
host cells.