Sentences with phrase «exocytosis results»
In Neu1 - deficient mice the excessive lysosomal exocytosis results in cleavage of VCAM - 1, loss of bone marrow progenitor cells from the bone niche and the onset of spleenic hematopoiesis.
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This led to decreased exocytosis of ATP from astrocytes, resulting in decreased purinergic signaling on dopaminergic neurons.
In these cells, glucose metabolism inhibits the ATP - dependent potassium channel (KATP channel) and opens voltage - dependent calcium channels (VDCCs), resulting in the exocytosis of insulin - containing granules [41].
Rothman immediately realised the importance of the result, and proposed the «SNARE hypothesis» for vesicle transport and exocytosis as a general process in all cell types: vesicle proteins specifically bind to target proteins in the plasma membrane to form a «v - t» complex which is necessary for vesicle and membrane fusion to proceed.
T11 / CD2 activation of cloned human natural killer cells results in increased conjugate formation and exocytosis of cytolytic granules.