Sentences with phrase «expanded huntingtin»

But this new information is an important addition to our knowledge of how expanded huntingtin behaves in the brain.

In the case of an expanded huntingtin gene, the RNA copy of the recipe is also expanded.

Bates» team showed that a protein usually responsible for the editing of RNA message molecules actually sticks to expanded huntingtin RNA, but not to normal huntingtin RNA.

But in mice engineered to carry an expanded huntingtin gene, the first non-coding region was not removed properly.

Not exact matches

The expanded CAG sequence in the HD gene results in a huntingtin protein with too many glutamines at the start of it.

The genetic basis of Huntington's disease (HD) is the presence of expanded CAG repeats in the huntingtin gene.

Studying mice, Bates» team has found that the splicing step, where the non-coding gibberish is removed from the RNA message, goes wrong if the huntingtin RNA is expanded, as it is in Huntington's disease.