Sentences with phrase «experimental infection models»
MAIT cells accumulate at the site of bacterial infection and are protective in experimental infection models.
https://science.institut-curie.org/ Not exact matches
In human donor cells and mouse experimental models, the researchers demonstrated that TSLP specifically targeted neutrophils — white blood cells that constitute the first line of defense against bacterial infections.
He had no animal model of the infection to use in his studies — rats and mice are not susceptible — so he famously used an experimental subject that did not require ethics approval or special funding: himself.
Experimental animal models have been used to investigate many aspects of the clinical disease such as the sex bias in myocarditis where testosterones in males promote autoimmunity in the heart while estrogens in females suppress virus infection and autoimmunity.
In addition, several reports suggest involvement in the activation of the immune response upon viral infection (Lupfer et al., 2013) and the requirement for the NOD2 / RIPK2 molecular pathway in several models on inflammatory diseases, including experimental colitis (Branquinho et al., 2016) and arthritis (Vieira et al., 2012).
Progress towards the development of highly effective vaccines for malaria has been frustratingly slow, but a distinctive bright spot for malaria vaccine and immunology researchers is the availability of human experimental models of P. falciparum - infection and malaria immunity.
• GRK 2046: «Parasite Infections: From Experimental Models to Natural Systems» • iGRK 2290: «Crossing Boundaries: Molecular Interactions in Malaria» • GRK 2318: «Tight junctions and their proteins: molecular features and actions in health and disease» • International Max - Planck Research School for Infectious Diseases and Immunology» (IMPRS - IDI)