Sentences with phrase «experimental therapies for»

We pursued chemo and a couple of experimental therapies for Raven, as well as holistic alternatives, but on Sept. 26, 2005, we lost her - only four months after the very first sign she was ill.

The lack of an animal model has also prevented scientists from testing and fine - tuning experimental therapies for people.

When the World Health Organization recently named blood transfusions from Ebola survivors as its priority experimental therapy for the disease ravaging west Africa there was only one major problem: no data indicating that such transfusions work.

«Experimental therapy for Prader - Willi syndrome shows promise in mice: Strategy activates silenced genes.»

Japanese researchers report promising results from an experimental therapy for Parkinson's disease that involves implanting neurons made from «reprogrammed» stem cells into the brain.

University of Pennsylvania immunotherapy researcher Dr. Carl June, who led the development of an experimental therapy for advanced childhood leukemia that is expected to become the first CAR T - cell therapy to win U.S. Food and Drug Administration approval, will give the keynote talk today at the Conference on Cell & Gene Therapy for HIV Cure at Fred Hutchinson Cancer Research Center.

Not exact matches

But the initiative comes with another huge financial prize for firms that successfully win FDA approval for these niche therapies: a priority review voucher that can be used to slash the regulatory period for a different experimental specialty treatment being developed by a drug maker or, more often, sold for potentially hundreds of millions of dollars to another pharma company.

Bellicum is among the flurry of biotechs investing heavily into cell therapies such as experimental chimeric antigen receptor T - cell (CAR - T) treatments for cancer (this is the next - gen treatment that involves reprogramming immune cells to become cancer killers and has shown promise in blood cancers, which Bellicum specializes in).

Gilead's R&D team brought home a clean sweep for its four Phase III studies adding the experimental drug bictegravir to its backbone HIV therapy.

The couple, both in their 30s and from Bedfont, west London, want to take the baby to a hospital in the US for experimental treatment, but lost a lengthy legal battle after judges ruled in favour of doctors at GOSH, who argued the therapy would not improve Charlie's quality of life.

Dietary medium - chain triglycerides prevent chemically induced experimental colitis in rats: Medium chain triglycerides show promise for nutritional therapy of inflammatory bowel disease (e.g., Crohn's disease and colitis) as an anti-inflammatory nutrient in the colon.

Enteral diets enriched with medium - chain triglycerides and N - 3 fatty acids prevent chemically induced experimental colitis in rats: Medium chain triglycerides (MCTs) and Omega 3s (found in flaxseed and cod liver oils) could be effective nutritional therapy for inflammatory bowel disease (e.g., Crohn's Disease, Colitis) due to this blend's anti-inflammatory effects.

Now, Emily has remained cancer - free for almost five years and her parents have created a foundation to help other patients access experimental cancer therapies.

It also provides novel insight into human mesenchymal stem cell - heart cell interactions that can guide future experimental studies to understand the mechanisms underlying mesenchymal stem cell therapy for the heart.

«It may sound like an appealing idea to allow seriously ill patients accelerated access to experimental therapies,» Sally Temple, the president of the International Society for Stem Cell Research, wrote to Texas lawmakers this month.

The study, «AKR1B1 promotes basal - like breast cancer progression by a positive feedback loop that activates the EMT program,» which has been published in The Journal of Experimental Medicine, suggests that an inhibitor of this enzyme currently used to treat diabetes patients could be an effective therapy for this frequently deadly form of cancer.

But for now, its top target is stopping HB 3236, which would open the door to patients paying for experimental therapies.

The experimental therapy, which involves administering a drug currently used in cancer therapy trials, treats cocaine addiction by inhibiting memories responsible for cravings.

This episode highlights a growing challenge for patients: how to temper enthusiasm for experimental therapies, now widely and effectively marketed through personal testimonials posted online, until evidence shows that the treatments are likely to do more good than harm.

A year after a government - appointed committee gave the green light to gene therapy, Britain still has no mechanism for approving any experimental treatments.

And they would love for people in Sierra Leone, Guinea, and Liberia to have access to experimental therapies as well, as the death toll from the largest Ebola outbreak on record climbs past 600.

The second team is lead by Bob Williamson at St Mary's Hospital Medical School and Duncan Geddes at the Royal Brompton Hospital, both in London, who want to test an experimental gene therapy for cystic fibrosis.

However, if there is no approved treatment for an ailment, the FDA has a compassionate therapy exception that allows the patient to agree to try an experimental approach.

Gene therapy death The Food and Drug Administration stopped a gene therapy trial this week after a patient undergoing the experimental treatment for a severe form of arthritis had a fatal reaction.

But in the meantime, it would help if we could identify who won't benefit from standard treatment, so we can spare them the debilitating effects of chemotherapy and get them into clinical trials for experimental therapies that might be more effective.»

Experimental and unregulated stem cell therapies have resulted in brain tumors, for example, as well as bones growing in eyelids.

Although several experimental trials of gene therapy are under way, some of them for more than a decade, uniQure is the first in the West to win regulatory approval for a commercial treatment.

For more than two decades, researchers have explored using gene therapy, an experimental treatment, to replace the flawed gene with a healthy copy.

Scientists from VIB and KU Leuven, together with colleagues from the University of California and the Swiss Institute for Experimental Cancer Research have demonstrated that, anti-angiogenic therapy can improve immune boosting treatments.

Since 2011, though, experimental CAR T cell treatments for B cell leukemias and lymphomas — cancers in which patients» healthy B cells turn cancerous — have been successful in some patients for whom all standard therapies had failed.

That would be a huge boon for therapy by allowing doctors to combine visual imaging, such as MRI scans, of tumors with knowledge of their genetic make - up, says experimental oncologist Janusz Rak of McGill University Health Centre in Montreal, Canada.

Cell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etc.).

An experimental protocol surgery using gene therapy to treat Alzheimer's disease is performed for the first time in the nation.

«Many optogenetic experimental designs can now be applied to completely normal tissues or animals, greatly extending the scope of these research tools and possibly allowing for new therapies involving neuronal photostimulation.»

University of California San Francisco researchers may have discovered why the experimental anti-cancer drug Onyx - 015 works more broadly than had been expected, a finding that could solidify and expand use of the drug and which reveals a potential new target for therapy that could prompt the development of other cancer drugs.

He volunteered for experimental gene therapy to correct it.

The potential for cell therapy to play a role in the therapy of myelin disorders is under serious consideration, based on years of experimentation of glial cell transplants in experimental models.

An experimental gene therapy for HIV may actually be easier — and even safer — than experts originally hoped.

Alain Destexhe, Research Director of Unité de Neurosciences CNRS, Gif - sur - Yvette, France Bruno Weber, Professor of Multimodal Experimental Imaging, Universitaet Zuerich, Switzerland Carmen Gruber Traub, Fraunhofer, Germany Costas Kiparissides, Certh, Greece Cyril Poupon, Head of the Nuclear Magnetic Resonance Imaging and Spectroscopy unit of NeuroSpin, University Paris Saclay, Gif - sur - Yvette, France David Boas, Professor of Radiology at Massachusetts General Hospital, Harvard Medical School, University of Pennsylvania Hanchuan Peng, Associate Investigator at Allen Brain Institute, Seattle, US Huib Manswelder, Head of Department of Integrative Neurophysiology Center for Neurogenomics and Cognitive Research, VU University, Amsterdam Jan G. Bjaalie, Head of Neuroinformatics division, Institute of Basic Medical Sciences, University of Oslo, Norway Jean - François Mangin, Research Director Neuroimaging at CEA, Gif - sur - Yvette, France Jordi Mones, Institut de la Macula y la Retina, Barcelona, Spain Jurgen Popp, Scientific Director of the Leibniz Institute of Photonic Technology, Jena, Germany Katharina Zimmermann, Hochshule, Germany Katrin Amunts, Director of the Institute Structural and functional organisation of the brain, Forschungszentrum Juelich, Germany Leslie M. Loew, Professor at University of Connecticut Health Center, Connecticut, US Marc - Oliver Gewaltig, Section Manager of Neurorobotics, Simulation Neuroscience Division - Ecole Polytechnique fédérale de Lausanne (EPFL), Geneve, Switzerland Markus Axer, Head of Fiber architecture group, Institute of Neuroscience and Medicine (INM - 1) at Forschungszentrum Juelich, Germany Mickey Scheinowitz, Head of Regenerative Therapy Department of Biomedical Engineering and Neufeld Cardiac Research Institute, Tel - Aviv University, Israel Pablo Loza, Institute of Photonic Sciences, Castelldefels, Spain Patrick Hof, Mount Sinai Hospital, New York, US Paul Tiesinga, Professor at Faculty of Science, Radboud University, Nijmegen, Netherlands Silvestro Micera, Director of the Translational Neural Engineering (TNE) Laboratory, and Associate Professor at the EPFL School of Engineering and the Centre for Neuroprosthetics Timo Dicksheid, Group Leader of Big Data Analytics, Institute Structural and functional organisation of the brain, Forschungszentrum Juelich, Germany Trygve Leergaard, Professor of Neural Systems, Institute of Basic Medical Sciences, University of Oslo, Norway Viktor Jirsa, Director of the Institute de Neurosciences des Systèmes and Director of Research at the CNRS, Marseille, France

He has extensive experience with the development of experimental vaccines for both genital herpes and HIV, and his lab has pioneered novel tests for diagnosing and monitoring therapies for viral infections.

In the next several years, when the laboratory process for recreating micro tumors is fast and reliable, Dr. Simeone expects to offer a Phase 1 clinical trial to design tailored single and combination therapies, as well as experimental agents targeting specific mutations.

Looking ahead, Swoboda, now one of the four site directors for Isis's phase 1 trial, expects more from the experimental splicing - directed therapy.

Clinical research activities are focused on the implementation of experimental protocols based on gene or cell therapy for the treatment of genetic blood disorders such as ADA - SCID, Wiskott - Aldrich Syndrome, Metachromatic Leukodystrophy, Beta - thalassemia, Chronic granulomatous disease, Mucopolysaccharidosis Type I (Hurler).

«The development of a functional human kidney glomerulus chip opens up an entirely new experimental path to investigate kidney biology, carry out highly personalized modeling of kidney diseases and drug toxicities, and the stem cell - derived kidney podocytes we developed could even offer a new injectable cell therapy approach for regenerative medicine in patients with life - threatening glomerulopathies in the future,» said Ingber.

For some it is a chance to gain access to experimental therapies.

More than a dozen experimental clinical therapies and vaccines have been developed from research from the Weiner laboratory, including the first Zika vaccine in clinical trials, as well as a novel immunotherapy for HPV - associated cancer and precancer.

Experimental results from this study could potentially lead to new therapies for lowering eye pressure in patients with primary open - angle glaucoma.

We chose to highlight a diverse set of biological processes and experimental systems to make the point that the principles of cross species analysis of basic gene function extend to the study of all human disorders, and can lead to mechanistic understanding of disease pathogenesis and rationale for the development of new therapies.

In contrast, therapeutic ketogenic diets used for epilepsy or as experimental cancer therapy often restrict carbs to fewer than 5 % of calories or fewer than 15 grams per day to further drive up ketone levels (9, 10).

Resistance Training for Diabetes Prevention and Therapy: Experimental Findings and Molecular Mechanisms.