Sentences with phrase «experimental use of these drugs»

Not exact matches

But the initiative comes with another huge financial prize for firms that successfully win FDA approval for these niche therapies: a priority review voucher that can be used to slash the regulatory period for a different experimental specialty treatment being developed by a drug maker or, more often, sold for potentially hundreds of millions of dollars to another pharma company.

The biotech plans to shed 20 % of its nearly 600 employees in order to secure yearly cost - savings of about $ 21 million — money which can then be used to double down on late - stage clinical trials for its experimental Parkinson's drug.

We do this by conducting clinical trials in which we collect safety and efficacy data about our experimental drugs with the goal of submitting those data to regulatory authorities, like the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), so that these experimental drugs can be approved for use by patients.

Nevertheless, when one reads, for instance, of how the Eli Lilly company used homeless alcoholics for testing experimental drugs, it is hard not to believe that such guinea pigs are being exploited, even if they may welcome their improved living conditions during the course of the research.

The researchers, however, also found that it may be possible to mitigate these effects with the use of an experimental class of drugs that can block stress.

The announcement comes amid a debate over the use of experimental drugs in the outbreak: a leading epidemiologist hopes the announcement will shift international focus toward relying on basic public health measures to control the disease.

WHO said on 6 August that it will convene an expert meeting next week to discuss the ethics of using untested treatments against the outbreak, and the Food and Drug Administration (FDA) removed a barrier to the use of another experimental medicine, TKM - Ebola, made by Tekmira of Burnaby, Canada.

If it were classified as a tissue instead, doctors could avoid some of the barriers to using experimental drugs while still requiring screening and other safety processes, the authors argue.

The experimental pilot study evaluated the use of magnet - directed nanoparticles containing the local anesthetic drug ropivacaine (MNP / Ropiv) to produce anesthesia of the limbs.

Although most of the shortages affect old, generic drugs, clinical trials often use these staples, either as controls or in combination with experimental medicines, including the genetically targeted drugs that many hope will revolutionize cancer care.

Furthermore, there are no differences between the major political party affiliation groups on views about the use of animals in research, the safety of eating genetically modified (GM) foods and whether to allow access to experimental drug treatments before those treatments have been shown to be safe and effective.

In April, a Clinical Center employee had noticed what appeared to be a fungal contamination in a vial of albumin — used in the administration of the drug interleukin in experimental studies — after being unable to draw the liquid out of the vial.

Some people enrolled in clinical trials with the U.S. National Institutes of Health (NIH) are continuing the use of experimental drugs despite the possibility the compounds have fungal contaminations.

Cell transplantation as a treatment for diabetes is still essentially experimental, uses cells from cadavers, requires the use of powerful immunosuppressive drugs, and has been available to only a very small number of patients.

In a study led by Duke Health and published in the journal Alcoholism: Clinical and Experimental Research, scientists demonstrate in rats that a short duration of the drug donepezil can reverse both structural and genetic damage that bouts of alcohol use causes in neurons, or nerve cells, in the young brain.

The researchers hope that understanding the level of virus needed for transmission of infection will provide a useful reference point for the development of experimental drugs and vaccines and could be used to inform the endpoints for clinical trials evaluating such interventions.

This, combined with the relative rarity of infections that warrant the use of new antibiotics and the further FDA requirement that patients not receive other antibiotics before they get the experimental drug, has set the goal out of reach, argues David Shlaes, who runs Anti-Infectives Consulting in Stonington, Connecticut.

The researchers picked one such experimental drug called RITA — Reactivation of p53 and Induction of Tumor cell Apoptosis — and used it to treat mice for a few days after cardiac injury.

A detailed picture of a brain - boosting experimental drug could one day help researchers tailor it for use in human clinical trials.

But yesterday, the agency announced that it is convening a panel of medical ethicists to discuss whether experimental drugs or vaccines could be used after all.

Just a few weeks ago, WHO said that using any of the experimental drugs or vaccines in the pipeline simply wasn't in the cards, because none of them have been through a phase I clinical study, the type of trial in which medical products are tested on healthy volunteers to study their toxicity.

The Wikipedia page also linked to stories about twin 5 - year - old girls who in 2009 had become the first Americans to fight NPC with an experimental treatment called cyclodextrin — but only after their parents had spent years pressing for «compassionate use» of the investigational drug outside of a clinical trial.

The scientists developed whole - body models to simulate the fate of each drug after ingestion and validated the models using experimental data from scientific literature.

You report on the difficulties of finding replacement drugs for executions and hence the off - label and experimental use of fentanyl...

See all of Science's coverage of the Ebola outbreak, including the ethics of using experimental drugs, the potential of existing treatments, and the tale of Africa's first encounter with the virus.

Although the molecule used in this study isn't one of the molecules under clinical trial, Zlotnick said the mechanism sheds light on the behavior of the experimental drugs.

In several steps using a new strategy and a novel drug, Burkhard Becher's team from the Institute of Experimental Immunology at the University of Zurich has now succeeded in doing exactly this in the case of glioblastoma, one of the most dangerous brain tumors.

The research was conducted using three different groups of mice, an experimental group of germ - free mice which were free of intestinal bacteria since birth, a group of mice that had received antibacterial drugs for 5 consecutive days, and a control group of mice with naturally occurring intestinal flora.

, the researchers described the case of a man with an acute lung disorder, in which he received an experimental treatment involving the use of his own blood - derived cells and the drug erythropoietin, which stimulates the production of red blood cells.

An experimental diabetes drug could be used to end the agony of transplant rejection, British scientists said.

University of California San Francisco researchers may have discovered why the experimental anti-cancer drug Onyx - 015 works more broadly than had been expected, a finding that could solidify and expand use of the drug and which reveals a potential new target for therapy that could prompt the development of other cancer drugs.

13:55 - 14:15 Roger Olsson, Lund University, Dept. of Experimental Medical Science Using zebrafish larvae in phenotypic CNS drug discovery and toxicology evaluation

A UK military healthcare worker has today been discharged from the Royal Free hospital and declared free of Ebola after being the first person in the world to be treated using the experimental drug MIL 77.

These cells are either used for research purposes (e.g. experimental medicine testing toxicity of new drugs) or under research for potential future clinical use.

An experimental oral drug has lowered blood sugar levels and inflammation in mice with Type 2 diabetes, suggesting that the medication could someday be added to the arsenal of drugs used by millions of Americans with this disease, according to new research.

This toolbox can be used for a wide variety of applications including drug discrimination, validation of experimental medicine models and patient stratification.

They will use CRISPR genome - editing technology to correct or insert disease - causing mutations in experimental models, and screen for potential drug targets with the goal of correcting neuronal dysfunction caused by the mutations.

Next I was offered an experimental injectable drug, Lupron, which is used to decrease the body's production of both male and female hormones and is commonly prescribed for the treatment of prostate cancer.

She is brought back to life by Prof. Jack Crowley (Bruce Abbott) through the use of an experimental drug, as part of a program designed to turn her into an unstoppable warrior.

Such experimental designs are widely used to evaluate the efficacy of medical drugs prior to making such treatments available to the public.

In particularly stubborncases, the use of ivermectin, an experimental drug in cats, may be justified.

Along with the three primary options i.e. surgery, radiation & use of anti cancer drugs, many other options are now in experimental stages to treat dog cancers.

Andrew Baron wrote this week to James C. Mullen, chief executive of Cambridge, Mass. - based Biogen Idec, pleading with him to let his father use the experimental drug Tysabri.

Critical illness insurance works in a very simple way: if you are diagnosed with any of the critical illnesses listed in your policy and survive the waiting period (typically it is 30 days), you will receive a lump sum, also called critical illness benefits, that you can use towards any individual needs: critical illness treatment, experimental treatment abroad, drugs that are not covered under provincial plans or simply treating it as an additional income.

He has conducted numerous experimental evaluations of interventions to prevent tobacco, other drug use, high - risk sexual behavior, reading failure, and aggressive social behavior.

This study (NIDA #R01DA025616) is a randomized clinical trial (RCT) that will compare an experimental treatment (OutPatient Treatment for Adolescents) to an «active placebo» on key indices (drug use; mental health; behavioral, school, peer, and family functioning; and consumer satisfaction) from pre-treatment through 18 months in order to evaluate its efficacy for youth referred to outpatient treatment of co-occurring substance use and internalizing problems.