Not exact matches
The
experimental vaccine, described in next month's Nature Biotechnology, could lead to a human influenza
vaccine that
uses up to 1000 times less DNA than current
experimental vaccines.
The researchers hope that understanding the level of virus needed for transmission of infection will provide a useful reference point for the development of
experimental drugs and
vaccines and could be
used to inform the endpoints for clinical trials evaluating such interventions.
«
Using an
experimental vaccine on human beings in the middle of an outbreak in this case would not be ethical, feasible, or wise,» a WHO representative e-mailed Science on 16 July.
But yesterday, the agency announced that it is convening a panel of medical ethicists to discuss whether
experimental drugs or
vaccines could be
used after all.
Just a few weeks ago, WHO said that
using any of the
experimental drugs or
vaccines in the pipeline simply wasn't in the cards, because none of them have been through a phase I clinical study, the type of trial in which medical products are tested on healthy volunteers to study their toxicity.
In consultation with an international team of experts and the patient herself [an
experimental]
vaccine was administered which has not been
used previously humans.
The Obama administration has asked Congress to pass a continuing resolution that will give $ 30 million more dollars to CDC to
use through 11 December, and $ 58 million to the Department of Health and Human Services to support development of
experimental vaccines and treatments.
If there's any silver lining in this, we need to make sure that some of the therapeutics and
vaccines that have been on an
experimental level so far, that we really
use this opportunity to make sure we have tools, real - world, available tools for people, hopefully for this outbreak, but if not for this outbreak for the next outbreak, and make sure that we have something of worth that comes out of this.
But until last week, there appeared to be little hope that any
experimental drugs or
vaccines might be
used to control the infection.
Wessely, like many researchers in the field, believes that Gulf War illness arose from a combination of the stress of war, the
use of
experimental vaccines, and possibly exposures to environmental hazards such as oil - well fires.
As a postdoc, Taylor developed an innovative laboratory technique
using metallic additives and magnets to test
experimental vaccines to see which B cells bind to them.
The eosinophil component of infiltrates was very prominent in animals vaccinated with the
experimental vaccine preparations when compared to animals mock - vaccinated
using PBS, or those exposed earlier to live virus (figure 6); few to no eosinophils were seen in those lung sections.
Exclusion criteria included: significant current illness as indicated by history, examination and / or laboratory testing including complete blood counts, alanine aminotransferase (ALT) and serum creatinine; previous immunization with a rabies
vaccine or any
experimental vaccine; chronic
use of immunosuppressants; receipt of blood products during the previous 6 months; and allergy to substances present in the
vaccines.
2015 — Began a Phase 1b clinical trial of two
experimental Ebola
vaccines in Kampala, Uganda,
using Chimpanzee Adenovirus type 3 vector (ChAd3)
vaccines, co-developed by the VRC, National Institutes of Allergy and Infectious Diseases (NIAID) and GlaxoSmithKine.