Not exact matches
Nadeau also studies the potential impacts of climate change
on species around the globe, using
modeling, field observation and
experiments to predict where species are most vulnerable and determine how conservation groups can best mitigate the negative impacts of climate change
on animal populations.
They were able to do so by building
on an
experiment showing that grafting a peripheral nerve into the space between a severed spinal cord in an
animal model brought about nerve regeneration (albeit limited).
Signs of neuronal damage around plaques also varied depending
on the APOE variant the
animals received, and
experiments in a different Alzheimer's
model in which plaques appear more slowly showed that injection of APOE4 increased levels of free, soluble A-beta in the fluid that bathes the brain.
«The result was an extensive inhibition of tumor growth and prevention of metastasis to the lung in HER2 - positive
animal models of breast cancer,» notes Navasona Krishnan, Ph.D., a postdoctoral investigator in the Tonks lab who performed many of the
experiments and is lead author
on the paper reporting the results.
This unique international event will provide the attendees with an innovative program focused
on the best practices in the use of the mouse
model for biomedical and basic research; this program also addresses the item of continuing professional education consistent with the new European directive requirement for lab
animal protection in
experiments.
After years of
experimenting with FMD in
animal models and showing its benefits
on metabolism and life span, Dr. Longo's team analyzed the effects in a human clinical trial that was published earlier this year.
It appears that in the simian
model used by us, the liver injury caused by AFB1 is accentuated by simultaneous restriction of dietary protein and in
animals on such combined regimen preneoplastic lesions appear around 90 weeks of
experiment.