Sentences with phrase «express chimeric»

Extracts from the brains of FFI patients transmitted disease to transgenic mice expressing a chimeric human - mouse PrP gene about 200 days after inoculation and induced formation of the 19 - kilodalton PrPSc fragment, whereas extracts from the brains of familial and sporadic Creutzfeldt - Jakob disease patients produced the 21 - kilodalton PrPSc fragment in these mice.

Osteosarcoma: Evaluation of a Recombinant, Attenuated Listeria Monocytogenes Expressing a Chimeric Human Her2 / neu Protein (ADXS31 - 164c) in Dogs With Osteosarcoma in the Adjuvant Setting

Not exact matches

They will examine the safety and feasibility of administering cancer - fighting chimeric antigen receptor (CAR) T cells that have been reprogrammed to target the CD22 protein expressed by some leukemia cells.

Over the past two years, investigators from the Perelman School of Medicine at the University of Pennsylvania have reported results from a human trial in GBM using chimeric antigen receptor (CAR) T cell therapy, through which patients» own T cells were engineered to track down and kill cancer cells that express a tumor - specific protein known as EGFRvIII.

In the proposed project, Dr. Lampi Hermanson will produce NK cells from stem cells, inserting a chimeric antigen receptor (CAR) with the capacity to recognize mesothelin cells, which is expressed in 70 % of ovarian cancer patients.

We took advantage of technology for chloroplast genome transformation to introduce chimeric minigenes expressing transcripts with altered or divergent cis - elements.

We have introduced chimeric genes which express GFP in a variety of organelles within the plant cell in order to study the dynamics of cell organization.

To differentiate between vaccines, three vaccine preparations were simultaneously evaluated, the double - inactivated (formalin and UV) whole virus vaccine (DIV), the rDNA - expressed S protein vaccine (SV), and the previously evaluated chimeric viral - like particle vaccine (VLP) that had led to immunopathology with virus challenge [16], [17], [20].

Timelapse of the internalisation of a chimeric doublet of cells expressing an actin marker (LifeAct) in different colours (snapshots taken every 15 min)

HV cell lines constitutively expressing β - Geo from the CAG promoter (HV lacZ) were fractionated into V+S + and V − S + and their ability to contribute to chimeric embryos assayed by morula aggregation.

However, when challenged to differentiate immediately after purification, each exhibits strong lineage bias, with the endoderm marker - expressing fraction unexpectedly able to contribute to the extra-embryonic endoderm in chimeric embryos.

We then tracked the expression of CD45 and class I and class II molecules on HPC - derived cells in long - term chimeric Rag2γc − / − mice by gating for the GFP expressing cells.

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