Indeed, because eggs are large cells that are relatively easy to manipulate, they are one of the favored cell types used by biologists to
express foreign genes and to test gene function.
By
expressing foreign genes in target cell types, they hope to be able to specifically silence or activate cells of interest.
Not exact matches
When the team looked at what
gene signatures the RORγt - dependent ILCs
expressed, they found high expression of major histocompatibility complex class II (MHCII) protein, which some cells use to display
foreign proteins to the immune system and directly interact with T cells.
The scientists had strategically inserted these
foreign DNA «markers» at particular points along the genome, next to
genes expressed only in embryonic stem cells.